Nursing Paper Example on Ulcers

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Nursing Paper Example on Ulcers

Ulcers, open sores on skin or mucous membranes, can develop anywhere in the body but are commonly found in the gastrointestinal tract (peptic ulcers), mouth, and on legs (venous ulcers). This paper examines the causes, pathophysiology, types, symptoms, diagnostic procedures, treatments, and prevention methods for ulcers. It also reviews specific complications and preventive strategies for individuals at high risk.

Nursing Paper Example on Ulcers

Causes of Ulcers

  1. Helicobacter pylori Infection
    The leading cause of peptic ulcers is infection with Helicobacter pylori, a bacterium that weakens the stomach’s mucous lining, making it susceptible to acidic damage (Peterson, 2013). H. pylori infection accounts for approximately 90% of all duodenal ulcers and 70% of gastric ulcers globally (Suerbaum & Michetti, 2002).
  2. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
    Long-term use of NSAIDs, including ibuprofen and aspirin, disrupts the stomach’s protective mucus and prostaglandin production, increasing ulceration risk (Laine, 2001). NSAIDs are estimated to cause about 30% of peptic ulcer cases.
  3. Lifestyle and Other Contributing Factors
    While lifestyle factors like smoking, excessive alcohol intake, and stress do not directly cause ulcers, they worsen existing conditions and delay healing (Malfertheiner et al., 2009).

(Nursing Paper Example on Ulcers)

Pathophysiology of Ulcers

Peptic ulcers occur when the balance between the digestive fluids (acid and pepsin) and the stomach or duodenal mucosal defenses is disturbed. H. pylori infection initiates inflammation and damages the gastric epithelial cells, leading to increased gastric acid secretion. NSAIDs inhibit prostaglandins, essential compounds for mucosal defense and blood flow in the stomach lining. This imbalance results in acid erosion of the lining, forming an ulcer (Wallace & Ma, 2001).

Types of Ulcers

  1. Gastric Ulcers
    Gastric ulcers develop in the stomach lining and are commonly associated with H. pylori or NSAID use. Symptoms often include pain shortly after eating.
  2. Duodenal Ulcers
    These ulcers occur in the upper portion of the small intestine (duodenum). Duodenal ulcers are often more painful on an empty stomach and respond well to acid suppression treatments.
  3. Esophageal Ulcers
    Resulting from acid reflux, esophageal ulcers are located in the esophagus and cause pain during swallowing or after eating acidic foods.
  4. Mouth Ulcers
    Known as canker sores, mouth ulcers are usually benign, resulting from minor injury, stress, or nutritional deficiencies, though not related to H. pylori.
  5. Venous Ulcers
    Typically found on the lower legs, venous ulcers arise from poor blood circulation, especially in people with chronic venous insufficiency.

(Nursing Paper Example on Ulcers)

Signs and Symptoms

  1. Pain and Burning Sensation
    A major symptom of peptic ulcers is gnawing, burning pain in the upper abdomen, often occurring between meals.
  2. Bloating and Nausea
    Bloating and mild nausea are common in gastric ulcers, especially when the stomach is empty or after NSAID use.
  3. Loss of Appetite and Weight Loss
    Pain and discomfort associated with eating can lead to reduced appetite and unintentional weight loss.
  4. Bleeding
    Severe ulcers may bleed into the gastrointestinal tract, presenting with black or tarry stools, vomit resembling coffee grounds, or anemia symptoms.

Diagnosis of Ulcers

  1. Endoscopy
    An upper endoscopy is the preferred diagnostic tool, allowing direct visualization of the ulcer and biopsy collection if malignancy is suspected.
  2. H. pylori Testing
    Non-invasive tests, including the urea breath test, stool antigen test, and blood test, help detect H. pylori infection (Gisbert & Pajares, 2004).
  3. Barium Swallow X-Ray
    This imaging test may be used when endoscopy is unavailable, as it provides an outline of the digestive tract to locate abnormal growths or ulcers.

Treatment of Ulcers

  1. Antibiotic Therapy
    For ulcers caused by H. pylori, a combination of antibiotics such as clarithromycin and amoxicillin effectively eradicates the bacteria, thereby reducing recurrence risk (Wong & Wong, 2009).
  2. Proton Pump Inhibitors (PPIs)
    PPIs, such as omeprazole, reduce stomach acid production, allowing the ulcer to heal and providing symptomatic relief.
  3. H2-Receptor Antagonists
    Drugs like ranitidine reduce acid production and are commonly used in patients who cannot tolerate PPIs.
  4. Lifestyle Modifications
    Patients should avoid smoking, alcohol, and certain foods that can aggravate ulcer symptoms. Limiting NSAID use is also critical in preventing recurrence.
  5. Surgical Intervention
    Surgery is rarely needed but may be required in cases of perforated or bleeding ulcers or when other treatments have failed.

Complications of Ulcers

  1. Bleeding
    Ulcers may erode blood vessels, leading to gastrointestinal bleeding, a potentially life-threatening complication.
  2. Perforation
    Severe ulcers can perforate the stomach or intestinal wall, leading to peritonitis, a medical emergency that requires immediate surgical intervention.
  3. Gastric Outlet Obstruction
    Chronic ulcers may cause swelling or scarring that blocks the passage of food, leading to vomiting, weight loss, and a need for surgical correction.
  4. Increased Cancer Risk
    Chronic H. pylori infection is a risk factor for gastric cancer. Monitoring and eradicating the bacterium can lower this risk (Peek & Blaser, 2002).

Prevention of Ulcers

  1. Eradication of H. pylori
    Screening and treating H. pylori infections is crucial for preventing ulcer recurrence, especially in patients with a history of peptic ulcers (Malfertheiner et al., 2009).
  2. Safe NSAID Usage
    Limiting NSAID use or taking these drugs with a protective agent like a PPI can prevent ulcers, especially in at-risk populations (Lanas et al., 2011).
  3. Healthy Lifestyle Practices
    Avoiding smoking, managing stress, and reducing alcohol intake can improve ulcer healing and decrease recurrence.
  4. Regular Medical Check-Ups
    High-risk individuals, such as those with a history of ulcers, are advised to have regular check-ups and possibly test for H. pylori if symptoms reoccur.

References

 
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