NR705-WEEK 2 Discussion-Prescreening Process

NR705-WEEK 2 Discussion-Prescreening Process

(NR705-WEEK 2 Discussion-Prescreening Process)

Name

Institution Affiliation

Course

Instructor

Practice Question

The following practice question will serve as the basis of the DNP project: For adults with a history of Schizophrenia (P) in the inpatient setting, does the implementation of technology with motivational interviewing (I), compared with current practice (C), impact medication nonadherence (O) in 8-10 weeks (T)? (NR705-WEEK 2 Discussion-Prescreening Process)

NR705-WEEK 2 Discussion-Prescreening Process

Process of Completing IRB Prescreening Supplement Form

Any project involving human participants requires IRB approval (Rooney et al., 2019). Chamberlain’s Institutional Review Board’s permission is needed to collect and or implement the DNP project, which involves schizophrenia patients, at the practicum site. The approval requires the filling of the IRB Prescreening Supplement. To complete the form, personal details are required, including student name, email, ID, project working title, practicum site name, preceptor’s name and contact, and key decision-makers’ contact details. The form is completed in various sections. Section I requires a description of the practice problem and the need for the project. Section II requires the provision of the practice question and the definition of the population. In section III, the student should provide a weekly implementation plan or protocol, generally, what will be done each week of the project implementation phase and the resources needed. Section IV requires describing a plan for educational offerings. Section V is the IRB completion that requires the student to thoroughly explain the data collection plan, measurable outcome identified in the practice question, names of tools and instruments used and their validity and reliability. In this section, the student should also elaborate a data analysis plan, identify statistical tests, plan to ensure participant’s confidentiality and safeguard data over time, and results dissemination plan.   The steps for the IRB prescreening review form include determining whether the project is “Research” as defined by the IRB, whether the project involves human subjects, whether the practice setting requires IRB review, and whether the project interacts with a vulnerable population. The last section of the IRB Prescreening Supplement Form involves confirmation of the various project aspects after completion. (NR705-WEEK 2 Discussion-Prescreening Process)

Data Collection Plan

Data will be collected pre-and post-intervention. A baseline measurement will be taken to determine the current state of medication nonadherence among schizophrenia patients. The Adherence Self-Report Questionnaire (ASRQ) will be used to collect this data. After the intervention has been fully implemented, a second measurement will be taken to determine medication adherence behavior changes among schizophrenia patients. The Adherence Self-Report Questionnaire (ASRQ) will collect post-intervention data for comparison with post-intervention data.

Zeller et al. (2008) Adherence Self-Report Questionnaire (ASRQ) is a tool used to collect information on medication adherence behavior. It has six levels, from level 1 = perfect adherence to level 6 = nonadherence, that determine an individual’s medication-taking behavior. It has six descriptions, and an individual is required to choose one of them: 1) “I always take all my tablets at the same time of the day;” 2) “I manage to take all my tablets – but not always at the same time of the day;” 3) “I sometimes do not take all my tablets, knowingly or unknowingly, but never omit more than one dose at a time;” 4) “I miss many tablets and about three to four times a year I miss my tablets, knowingly or unknowingly, for two or more days;” 5) “I miss many tablets, knowingly or unknowingly, and at least once a month I miss my tablets for two or more days;” 6) “I take hardly any of my schizophrenia tablets.” The authors of the ASRQ reported an 88.3% timing adherence. The tool registered a specificity between 90-93% and negative predictive value of 66-96% on those who comparatively had high adherence. However, the detection of true nonadherence had a poor to moderate sensitivity and positive predictive value, ranging between 22-66%. Conclusively, the ASRQ could be used to gather data on medication adherence behavior among schizophrenia patients. The tool is in the public domain. (NR705-WEEK 2 Discussion-Prescreening Process)

Project Status

The project is still in the approval stage, but the research team is working with participants towards data collection, which will only be completed after IRB approval. However, the preparation is necessary, including explaining to participants what is expected of them, the method, instruments and duration of data collection. Generally, the team is in the initial stages of the implementation, and the organization I am working with is already aware of the project implementation, the intervention, and the involvement of schizophrenia patients in the study. (NR705-WEEK 2 Discussion-Prescreening Process)

References

Rooney, L., Covington, L., Dedier, A., & Samuel, B. (2019). Measuring IRB Regulatory Compliance: Development, Testing, and Use of the National Cancer Institute StART Tool. Journal of empirical research on human research ethics: JERHRE14(2), 95–106. https://doi.org/10.1177/1556264619831888

Zeller, A., Schroeder, K., & Peters, T. J. (2008). An adherence self-report questionnaire facilitated the differentiation between nonadherence and nonresponse to antihypertensive treatment. Journal of clinical epidemiology61(3), 282–288. https://doi.org/10.1016/j.jclinepi.2007.04.007

 
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Nursing Paper Example on Palindromic Rheumatism [SOLVED]

Nursing Paper Example on Palindromic Rheumatism [SOLVED]

Palindromic rheumatism, a rare and perplexing condition, presents as recurrent episodes of joint inflammation, often without lasting damage. This enigmatic ailment, characterized by its unpredictable nature, challenges both patients and healthcare providers alike. Despite its mysterious presentation, significant strides have been made in understanding its underlying mechanisms and devising effective management strategies. In this paper, we embark on an exploration of palindromic rheumatism, shedding light on its causes, symptoms, diagnosis, and treatment options, aiming to equip healthcare professionals with the knowledge necessary to navigate this complex condition effectively. By delving into the intricate facets of palindromic rheumatism, we endeavor to unravel its mysteries and empower clinicians with the tools needed to provide optimal care for affected individuals. Through a comprehensive understanding of palindromic rheumatism, we can enhance patient outcomes and alleviate the burden imposed by this enigmatic rheumatic disorder. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

Nursing Paper Example on Palindromic Rheumatism [SOLVED]

Causes

Palindromic rheumatism is a condition whose precise origins remain elusive, prompting ongoing investigation and speculation within the medical community. While no singular cause has been definitively identified, several factors have been proposed to contribute to its development. Genetic predisposition emerges as a prominent contender in the etiology of palindromic rheumatism, with evidence suggesting familial clustering and genetic variations associated with immune dysregulation. Environmental triggers, including infections and physical trauma, are also implicated in precipitating the onset of symptoms in susceptible individuals. The interplay between genetic susceptibility and environmental factors underscores the multifactorial nature of palindromic rheumatism, highlighting the complex mechanisms underlying its pathogenesis.

Autoimmune mechanisms have garnered significant attention in the quest to unravel the origins of palindromic rheumatism. Dysregulation of the immune system, characterized by aberrant responses targeting synovial tissue, is postulated to play a pivotal role in driving inflammation and joint pathology. Evidence of elevated levels of inflammatory mediators, such as cytokines and chemokines, further supports the involvement of autoimmune processes in the pathophysiology of palindromic rheumatism.

Moreover, hormonal factors have been proposed as potential contributors to the development of palindromic rheumatism, with some studies suggesting a predilection for onset or exacerbation of symptoms during specific hormonal fluctuations, such as pregnancy or menopause. The intricate interplay between genetic, environmental, and hormonal factors underscores the multifaceted nature of palindromic rheumatism etiology, necessitating a comprehensive approach to understanding its underlying mechanisms. Despite ongoing research efforts, the precise interactions between these factors and their relative contributions to disease onset and progression remain areas of active investigation, warranting further exploration to elucidate the complex etiological landscape of palindromic rheumatism. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

Signs and Symptoms

Palindromic rheumatism manifests as recurrent episodes of joint inflammation, characterized by a constellation of symptoms that vary in intensity and duration. The hallmark feature of this condition is its episodic nature, with symptoms spontaneously resolving between flare-ups. Affected individuals commonly report pain, swelling, and stiffness in the affected joints, which can impair mobility and diminish quality of life during acute episodes. The joints most commonly involved include the wrists, fingers, knees, and ankles, although any joint in the body can be affected.

During episodes of inflammation, affected joints may exhibit signs of erythema and warmth, indicative of the underlying inflammatory process. These visual cues, coupled with palpable swelling and tenderness upon examination, contribute to the clinical diagnosis of palindromic rheumatism. Additionally, individuals may experience systemic symptoms, such as fatigue and malaise, during active flare-ups, further exacerbating the impact of the condition on daily functioning.

One of the distinguishing features of palindromic rheumatism is the transient nature of its symptoms, with joint inflammation typically subsiding spontaneously within hours to days, only to recur at unpredictable intervals. This cyclical pattern of remission and relapse distinguishes palindromic rheumatism from other rheumatic conditions, such as rheumatoid arthritis, which typically exhibit a more chronic and progressive course.

Despite the transient nature of symptoms, the unpredictable recurrence of joint inflammation poses significant challenges for affected individuals, impacting their ability to engage in daily activities and maintain a consistent quality of life. Furthermore, the absence of lasting joint damage during early stages of the disease may obscure the diagnosis and delay initiation of appropriate management strategies. Thus, recognizing the characteristic signs and symptoms of palindromic rheumatism is essential for timely intervention and optimal patient outcomes. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

Etiology

The etiology of palindromic rheumatism remains a subject of ongoing investigation, characterized by a complex interplay of genetic, environmental, and immunological factors. Genetic predisposition emerges as a key contributor to the development of palindromic rheumatism, with evidence suggesting familial clustering and heritability of the condition. Studies have identified genetic variations associated with immune dysregulation and inflammatory pathways, implicating inherited susceptibility in the pathogenesis of the disease.

Environmental triggers also play a significant role in precipitating the onset of palindromic rheumatism in genetically susceptible individuals. Infections, particularly viral and bacterial pathogens, have been implicated as potential triggers for inflammatory responses in susceptible individuals. Physical trauma or injury to joints may also serve as precipitating factors, triggering inflammatory cascades and exacerbating symptoms in predisposed individuals.

The immune system’s dysregulated response to environmental triggers is thought to play a central role in the pathogenesis of palindromic rheumatism. Aberrant activation of immune cells, such as T lymphocytes and macrophages, leads to the production of inflammatory mediators, including cytokines and chemokines, which perpetuate joint inflammation and tissue damage. Dysregulation of regulatory mechanisms that normally maintain immune homeostasis may further exacerbate the inflammatory process, contributing to the episodic nature of the disease.

Additionally, hormonal factors have been proposed as potential contributors to the development of palindromic rheumatism. Fluctuations in hormone levels, such as estrogen and progesterone, during specific life stages, such as pregnancy or menopause, may influence disease activity and symptom severity in susceptible individuals. The intricate interplay of genetic, environmental, and hormonal factors underscores the multifactorial nature of palindromic rheumatism etiology, highlighting the complex mechanisms underlying its pathogenesis. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

Pathophysiology

The pathophysiology of palindromic rheumatism is characterized by complex immunological processes that drive recurrent episodes of joint inflammation. Central to the pathogenesis of the disease is the dysregulation of the immune system, leading to aberrant immune responses targeting synovial tissue. Upon exposure to environmental triggers or endogenous stimuli, such as infections or tissue injury, immune cells, including T lymphocytes and macrophages, become activated and infiltrate the synovium, initiating an inflammatory cascade.

Nursing Paper Example on Palindromic Rheumatism [SOLVED]

Inflammatory mediators, such as cytokines (e.g., tumor necrosis factor-alpha, interleukins) and chemokines, play a pivotal role in orchestrating the inflammatory response within the joints. These molecules promote the recruitment and activation of additional immune cells, perpetuating inflammation and contributing to tissue damage. Dysregulation of pro-inflammatory cytokines and imbalance in the production of anti-inflammatory mediators disrupts immune homeostasis, exacerbating joint inflammation and symptomatology.

Furthermore, the synovial membrane undergoes hyperplasia and vascular proliferation in response to inflammatory stimuli, leading to synovitis and the characteristic swelling observed during acute flares of palindromic rheumatism. The synovial fluid becomes infiltrated with inflammatory cells, including neutrophils and lymphocytes, further perpetuating the inflammatory milieu within the joint space.

Chronic inflammation within the synovium and surrounding tissues can result in progressive joint damage, characterized by cartilage degradation, bone erosion, and joint deformities. Despite the absence of persistent inflammation between episodes, repeated bouts of acute inflammation may contribute to cumulative joint damage over time.

The episodic nature of palindromic rheumatism, characterized by alternating periods of inflammation and remission, reflects the dynamic interplay between environmental triggers, immune dysregulation, and inflammatory mediators. Understanding the underlying pathophysiological mechanisms of palindromic rheumatism is essential for developing targeted therapeutic interventions aimed at modulating the immune response and mitigating joint damage in affected individuals. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

DSM-5 Diagnosis

Diagnosing palindromic rheumatism poses a considerable challenge due to its episodic nature and lack of specific diagnostic markers within the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Instead, diagnosis relies on a comprehensive clinical assessment, which includes a thorough medical history, physical examination, and exclusion of other rheumatic conditions with similar presentations.

During the initial evaluation, healthcare providers gather information regarding the onset, duration, and characteristics of joint symptoms experienced by the patient. Key features suggestive of palindromic rheumatism include recurrent episodes of joint inflammation, typically involving multiple joints, and a pattern of remission and relapse between flare-ups.

Physical examination may reveal signs of joint inflammation, such as swelling, tenderness, erythema, and warmth, in the affected joints. However, it is essential to note that these findings may be absent during interictal periods, further complicating the diagnostic process.

Laboratory tests, including inflammatory markers such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), may be elevated during acute flares of inflammation, supporting the diagnosis. However, normal laboratory findings do not exclude the possibility of palindromic rheumatism, as these markers may fluctuate or remain within normal limits between episodes.

Imaging studies, such as X-rays and ultrasound, may be performed to assess for evidence of joint damage or inflammation. While these modalities can aid in supporting the diagnosis, they are not specific to palindromic rheumatism and may show nonspecific findings or be normal in early stages of the disease.

Given the absence of specific diagnostic criteria in the DSM-5, a multidisciplinary approach involving rheumatologists, internists, and other healthcare providers is essential for accurately diagnosing palindromic rheumatism and differentiating it from other rheumatic conditions with similar presentations. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

Treatment Regimens and Patient Education

Management of palindromic rheumatism aims to alleviate symptoms, prevent joint damage, and improve overall quality of life through a combination of pharmacological and non-pharmacological interventions. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, are commonly used to alleviate pain and reduce inflammation during acute flares. These medications can provide symptomatic relief and improve joint function, but their long-term use may be associated with gastrointestinal and cardiovascular side effects.

In cases of more severe or refractory disease, disease-modifying antirheumatic drugs (DMARDs) may be initiated to suppress inflammation and prevent disease progression. Methotrexate, hydroxychloroquine, and sulfasalazine are among the DMARDs commonly prescribed for palindromic rheumatism. These medications work by modulating the immune response and reducing the frequency and severity of flares. Close monitoring for potential adverse effects, including hepatotoxicity and bone marrow suppression, is essential when using DMARDs.

Corticosteroids may be used as adjunctive therapy for acute exacerbations of palindromic rheumatism to rapidly suppress inflammation and alleviate symptoms. However, their long-term use is generally discouraged due to the risk of adverse effects, including osteoporosis, hypertension, and glucose intolerance.

In addition to pharmacological interventions, lifestyle modifications play a crucial role in managing palindromic rheumatism and promoting overall well-being. Regular exercise, including low-impact activities such as swimming or cycling, can help improve joint flexibility, strength, and mobility while reducing pain and stiffness. Maintaining a healthy weight and adopting ergonomic principles in daily activities can also alleviate strain on the joints and minimize the risk of exacerbating symptoms.

Patient education is paramount in empowering individuals with palindromic rheumatism to manage their condition effectively and optimize treatment outcomes. Healthcare providers play a crucial role in educating patients about the nature of the disease, including its episodic course, potential triggers, and available treatment options. Emphasizing the importance of medication adherence, regular follow-up appointments, and self-management strategies, such as joint protection techniques and stress management, can help patients better cope with the challenges posed by palindromic rheumatism and improve their quality of life. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

Conclusion

Palindromic rheumatism presents as a perplexing condition characterized by recurrent episodes of joint inflammation, challenging both patients and healthcare providers. Despite its elusive nature, significant progress has been made in understanding its causes, symptoms, diagnosis, and treatment options. Through an exploration of its multifactorial etiology, complex pathophysiology, and multidisciplinary management approaches, this paper has provided valuable insights into navigating the complexities of palindromic rheumatism. By emphasizing the importance of patient education, lifestyle modifications, and pharmacological interventions, healthcare professionals can empower individuals with palindromic rheumatism to effectively manage their condition and improve their quality of life. Continued research efforts are essential to further unraveling the mysteries surrounding palindromic rheumatism and developing novel therapeutic strategies aimed at mitigating joint inflammation and preventing long-term complications. With a comprehensive understanding of palindromic rheumatism, healthcare providers can better support patients in their journey towards symptom control and enhanced well-being. (Nursing Paper Example on Palindromic Rheumatism [SOLVED])

References

https://pubmed.ncbi.nlm.nih.gov/25558613/#:~:text=A%20patient%20suffering%20from%20palindromic,peptide%20antibodies%20(positive%20in%20approx.

 
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Nursing Paper Example on Myxedema [SOLVED]

Nursing Paper Example on Myxedema [SOLVED]

Myxedema represents a severe, advanced form of hypothyroidism, characterized by significant metabolic derangements and distinct physical symptoms. This condition often results from untreated or inadequately managed hypothyroidism, leading to life-threatening complications if not promptly addressed. Myxedema can develop due to various underlying causes, including autoimmune disorders, thyroid gland removal, or exposure to certain medications. Its symptoms are profound and can affect multiple organ systems, manifesting as fatigue, skin changes, and cardiovascular abnormalities. Understanding the etiology and pathophysiology of myxedema is crucial for accurate diagnosis and effective treatment. This paper explores the comprehensive aspects of myxedema, including its causes, signs and symptoms, etiology, pathophysiology, DSM-5 diagnostic criteria, treatment regimens, and essential patient education. By delving into these areas, we aim to enhance awareness and improve outcomes for individuals affected by this serious thyroid condition. (Nursing Paper Example on Myxedema [SOLVED])

Nursing Paper Example on Myxedema [SOLVED]

Causes

Myxedema arises primarily from severe, untreated hypothyroidism, which can develop due to several underlying factors. The most common cause is autoimmune thyroiditis, also known as Hashimoto’s thyroiditis. In this condition, the immune system mistakenly attacks the thyroid gland, leading to its gradual destruction and a subsequent decline in thyroid hormone production. This autoimmune process is the leading cause of hypothyroidism in developed countries.

Another significant cause of myxedema is the surgical removal of the thyroid gland, known as thyroidectomy. This procedure may be necessary to treat thyroid cancer, severe hyperthyroidism, or large goiters that cause compressive symptoms. Following thyroidectomy, patients often require lifelong thyroid hormone replacement therapy. Failure to adhere to this treatment regimen can result in the development of myxedema.

Radioactive iodine therapy, used to treat hyperthyroidism, can also lead to hypothyroidism and subsequently myxedema. This treatment works by destroying overactive thyroid tissue but can sometimes impair the gland’s ability to produce adequate hormones, necessitating hormone replacement therapy.

Certain medications are known to induce hypothyroidism and may contribute to myxedema if not monitored properly. Drugs such as lithium, used for bipolar disorder, and amiodarone, used for cardiac arrhythmias, can interfere with thyroid function. Patients taking these medications should have their thyroid function regularly checked to prevent severe hypothyroidism.

Additionally, secondary causes of myxedema include pituitary or hypothalamic disorders that impair the production of thyroid-stimulating hormone (TSH). Without adequate TSH, the thyroid gland is not sufficiently stimulated to produce hormones, leading to hypothyroidism.

Environmental factors, such as severe iodine deficiency, can also contribute to the development of myxedema. Iodine is essential for thyroid hormone synthesis, and a lack of it in the diet can lead to inadequate hormone production. This is more common in areas where iodine deficiency is prevalent.

Understanding these diverse causes is crucial for the prevention and effective management of myxedema, ensuring patients receive appropriate treatment and monitoring. (Nursing Paper Example on Myxedema [SOLVED])

Signs and Symptoms

Patients with myxedema exhibit a variety of symptoms that reflect severe hypothyroidism. These symptoms can affect multiple organ systems, leading to a range of clinical manifestations. Profound fatigue is one of the most common symptoms, with patients often feeling extremely tired and lethargic, even after adequate rest. This fatigue can significantly impair daily functioning and quality of life.

Weight gain is another frequent symptom of myxedema. This occurs due to a slowed metabolism, which leads to reduced energy expenditure and increased fat storage. Patients may notice an unexpected and progressive increase in body weight despite maintaining their usual diet and activity levels.

Cold intolerance is also a hallmark of myxedema. Patients often feel unusually cold, even in warm environments, due to decreased heat production from a slowed metabolism. This symptom is often accompanied by dry, thickened, and swollen skin, particularly around the eyes and extremities. The skin changes are due to the accumulation of glycosaminoglycans in the dermis, leading to water retention and a puffy appearance.

Additionally, myxedema can cause significant changes in appearance. Patients may experience hair loss, with hair becoming thin and brittle. Hoarseness is another common symptom, resulting from the swelling of the vocal cords. The face may appear puffy and swollen, particularly around the eyes.

Cardiovascular symptoms are also notable in myxedema. Patients often present with bradycardia, a slow heart rate, and hypotension, low blood pressure. These symptoms can lead to reduced cardiac output and overall cardiovascular efficiency. In severe cases, pericardial effusion, the accumulation of fluid around the heart, can occur, further compromising cardiac function.

In extreme cases, myxedema coma can develop, which is a life-threatening condition. Symptoms of myxedema coma include hypothermia, altered mental status, and respiratory failure. Immediate medical intervention is crucial to prevent fatal outcomes. Recognizing these diverse symptoms is essential for the timely diagnosis and management of myxedema. (Nursing Paper Example on Myxedema [SOLVED])

Etiology

The etiology of myxedema involves various factors that lead to severe hypothyroidism. Primary hypothyroidism is the most common underlying cause, where the thyroid gland itself fails to produce adequate hormones. This failure is often due to autoimmune destruction, as seen in Hashimoto’s thyroiditis. In this condition, the body’s immune system targets thyroid cells, leading to inflammation and decreased hormone production over time.

Surgical removal of the thyroid gland, known as thyroidectomy, is another significant cause. This procedure is typically performed to treat thyroid cancer, hyperthyroidism, or large goiters. After the removal of the thyroid gland, patients require lifelong thyroid hormone replacement therapy. If this therapy is insufficient or not adhered to properly, severe hypothyroidism and myxedema can develop.

Radioactive iodine therapy, commonly used to treat hyperthyroidism, can also result in myxedema. This treatment destroys overactive thyroid tissue but can sometimes impair the gland’s ability to produce hormones sufficiently. This necessitates careful monitoring and potential hormone replacement to prevent myxedema.

Certain medications can contribute to the etiology of myxedema by interfering with thyroid function. For example, lithium, used to treat bipolar disorder, and amiodarone, used for cardiac arrhythmias, can disrupt normal thyroid hormone synthesis and regulation. Patients on these medications should be closely monitored for signs of hypothyroidism.

Secondary hypothyroidism, resulting from pituitary or hypothalamic disorders, can also lead to myxedema. In these cases, inadequate production of thyroid-stimulating hormone (TSH) fails to stimulate the thyroid gland, resulting in decreased hormone production.

Environmental factors, such as severe iodine deficiency, play a role in the development of myxedema as well. Iodine is a critical component of thyroid hormones, and a lack of dietary iodine can lead to insufficient hormone synthesis. This is particularly relevant in regions where iodine deficiency is common, highlighting the importance of adequate nutrition in preventing myxedema. (Nursing Paper Example on Myxedema [SOLVED])

Pathophysiology

The pathophysiology of myxedema is rooted in the critical role of thyroid hormones in regulating metabolism and cellular function. In severe hypothyroidism, the significant decrease in triiodothyronine (T3) and thyroxine (T4) levels leads to a marked reduction in metabolic activity. This metabolic slowdown affects nearly every organ system, resulting in the characteristic symptoms of myxedema.

One of the most notable features of myxedema is the accumulation of glycosaminoglycans in the dermis, which leads to water retention and tissue swelling. This accumulation occurs because thyroid hormones normally regulate the synthesis and degradation of these substances. Without adequate hormone levels, glycosaminoglycans build up, drawing water into the tissues and causing the thickened, puffy skin typical of myxedema.

Cardiovascular effects are significant in myxedema. The decreased metabolic rate leads to a reduction in cardiac output, as the heart pumps less blood with each beat. Bradycardia, or a slow heart rate, is common due to reduced sympathetic nervous system activity. Additionally, hypotension, or low blood pressure, can result from decreased peripheral vascular resistance. In severe cases, pericardial effusion, the accumulation of fluid around the heart, further impairs cardiac function and can lead to heart failure if not addressed.

Neurological manifestations are also prevalent in myxedema. The decreased central nervous system activity results in cognitive impairment, depression, and slowed reflexes. Severe hypothyroidism can lead to myxedema coma, characterized by hypothermia, altered mental status, and respiratory depression. This life-threatening condition requires immediate medical intervention.

Overall, the pathophysiology of myxedema involves a complex interplay of metabolic, cardiovascular, and neurological dysfunctions resulting from inadequate thyroid hormone levels. Understanding these mechanisms is crucial for diagnosing and managing this severe form of hypothyroidism effectively. (Nursing Paper Example on Myxedema [SOLVED])

DSM-5 Diagnosis

Myxedema is primarily a medical condition, but its impact on mental health is significant enough to warrant consideration in psychiatric evaluations. The DSM-5 does not list myxedema as a distinct psychiatric disorder, but it acknowledges that medical conditions, including severe hypothyroidism, can contribute to psychiatric symptoms.

Patients with myxedema often experience symptoms that overlap with various psychiatric conditions. Depression is a common presentation, characterized by persistent sadness, fatigue, and a lack of interest in daily activities. Cognitive impairment is also frequent, with patients experiencing memory loss, difficulty concentrating, and slowed thought processes. These symptoms can mimic major depressive disorder or dementia, complicating the diagnostic process.

In some cases, severe hypothyroidism can lead to myxedema psychosis, a condition marked by hallucinations, delusions, and severe mood disturbances. This psychosis is directly linked to the metabolic imbalances caused by inadequate thyroid hormone levels. Clinicians must consider thyroid function tests when encountering patients with new or worsening psychiatric symptoms, especially if these symptoms are resistant to standard psychiatric treatments.

The DSM-5 encourages a holistic approach to diagnosis, emphasizing the importance of identifying and addressing underlying medical conditions that may contribute to psychiatric symptoms. For patients with myxedema, this means that comprehensive thyroid function testing should be part of the diagnostic workup. Recognizing the connection between myxedema and psychiatric symptoms ensures that patients receive appropriate treatment for both their thyroid condition and mental health issues.

By incorporating medical evaluations into psychiatric assessments, clinicians can improve diagnostic accuracy and treatment outcomes. Effective management of myxedema involves treating the thyroid dysfunction, which often leads to significant improvements in psychiatric symptoms. This integrated approach underscores the importance of considering physical health in the context of mental health care. (Nursing Paper Example on Myxedema [SOLVED])

Treatment Regimens and Patient Education

Treatment of myxedema requires prompt and comprehensive intervention to address the underlying hypothyroidism and prevent complications. The cornerstone of therapy is thyroid hormone replacement, typically with levothyroxine. This synthetic form of thyroxine (T4) is administered orally and adjusted based on regular monitoring of thyroid function tests to ensure adequate hormone levels. In myxedema coma, a life-threatening condition, immediate hospitalization and intravenous administration of levothyroxine and liothyronine (T3) are crucial, along with supportive measures such as warming and ventilatory support.

For patients with severe hypothyroidism or myxedema coma, initial treatment may include a loading dose of levothyroxine to quickly restore hormone levels. This is followed by maintenance therapy tailored to the individual’s needs. Corticosteroids may also be administered initially to address potential adrenal insufficiency, which can coexist with severe hypothyroidism.

Patient education is vital for effective management of myxedema. Patients should be informed about the importance of adhering to their prescribed thyroid hormone replacement therapy. They need to understand that lifelong treatment is often necessary and that regular follow-up appointments are crucial to monitor thyroid function and adjust medication dosages as needed.

Patients should also be educated about recognizing the early signs of hypothyroidism, such as fatigue, weight gain, and cold intolerance, so they can seek timely medical attention. Additionally, they should be aware of the symptoms of myxedema coma, including severe lethargy, hypothermia, and respiratory difficulties, which require immediate emergency care.

Dietary considerations are also important. Patients should ensure they have sufficient iodine intake, as iodine is essential for thyroid hormone production. Foods rich in iodine, such as dairy products, seafood, and iodized salt, should be included in their diet. However, patients should also be cautioned against excessive iodine intake, which can negatively impact thyroid function.

Patients on medications that affect thyroid function, such as lithium or amiodarone, should have their thyroid levels closely monitored. They need to understand the potential impact of these medications on their thyroid health and the importance of regular blood tests.

Education about lifestyle factors, such as maintaining a healthy weight, regular exercise, and avoiding smoking, can also help improve overall health and well-being. Encouraging patients to maintain open communication with their healthcare providers ensures that any concerns or symptoms are promptly addressed, leading to better management of their condition.

Effective treatment and patient education are critical in managing myxedema and improving quality of life for affected individuals. (Nursing Paper Example on Myxedema [SOLVED])

Conclusion

Myxedema, a severe manifestation of hypothyroidism, requires timely and comprehensive medical intervention to prevent life-threatening complications. Understanding its causes, such as autoimmune thyroiditis, thyroidectomy, and certain medications, is essential for prevention and effective management. The distinctive symptoms, including profound fatigue, weight gain, cold intolerance, and cardiovascular and neurological impairments, necessitate early recognition and treatment. The pathophysiology involves significant metabolic, cardiovascular, and neurological dysfunctions due to inadequate thyroid hormone levels. While myxedema is not listed in the DSM-5, its impact on mental health, including depression and myxedema psychosis, underscores the need for integrated medical and psychiatric care. Treatment primarily involves thyroid hormone replacement therapy, with patient education focusing on adherence to medication, recognizing early symptoms, and ensuring adequate iodine intake. By combining effective treatment regimens with thorough patient education, healthcare providers can significantly improve outcomes and quality of life for individuals with myxedema. (Nursing Paper Example on Myxedema [SOLVED])

References

https://www.ncbi.nlm.nih.gov/books/NBK545193/

 
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Nursing Paper Example on Necrotizing Fasciitis [SOLVED]

Nursing Paper Example on Necrotizing Fasciitis [SOLVED]

Necrotizing Fasciitis (NF) presents a formidable challenge in the realm of infectious diseases, characterized by its rapid and destructive nature. Often referred to as the “flesh-eating disease,” NF instills fear due to its ability to swiftly ravage soft tissue and pose significant morbidity and mortality risks. This paper serves as a beacon of knowledge, illuminating the intricate facets of NF, from its insidious causes to its dire consequences. As we embark on this exploration, we delve into the labyrinth of NF’s pathogenesis, unraveling the complex interplay between bacterial pathogens and host defenses. By dissecting its clinical manifestations and diagnostic criteria, we strive to empower healthcare providers with the tools necessary for early recognition and intervention. Through a multifaceted approach encompassing both medical and surgical management strategies, we endeavor to mitigate the impact of NF and safeguard the well-being of those affected by this relentless adversary. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

Nursing Paper Example on Necrotizing Fasciitis [SOLVED]

Causes

Necrotizing Fasciitis (NF) arises from a consortium of bacterial pathogens, with group A Streptococcus (GAS) and Staphylococcus aureus being predominant culprits. These bacteria possess virulent traits that enable them to invade and rapidly proliferate within the subcutaneous tissues, precipitating the cascade of tissue destruction characteristic of NF.

Numerous predisposing factors can predispose individuals to NF, including immunocompromised states such as diabetes mellitus, chronic renal failure, or HIV infection. Additionally, conditions compromising the skin’s integrity, such as dermatologic conditions or recent trauma/surgery, create portals of entry for bacterial invasion.

Traumatic wounds, including lacerations, abrasions, or puncture injuries, serve as common entry points for NF-causing pathogens. Surgical incisions, particularly in contaminated or poorly perfused areas, can also become sites of infection. Intravenous drug use represents another risk factor, as repeated needle injections can introduce bacteria into the bloodstream, facilitating their dissemination to distant tissues.

Microbial synergy plays a crucial role in the pathogenesis of NF, with polymicrobial infections often contributing to its development. Bacterial toxins and enzymes produced by these pathogens synergistically potentiate tissue destruction, leading to the characteristic clinical features of NF.

Environmental factors may also influence the incidence of NF, with warmer climates and aquatic environments favoring the growth of certain bacteria implicated in NF, such as Vibrio species.

NF is a multifactorial disease process precipitated by the interplay of virulent bacterial pathogens, host predisposing factors, and environmental influences. Understanding these underlying causes is paramount for implementing preventive measures and prompt management strategies to mitigate the devastating consequences of NF. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

Signs and Symptoms

The clinical presentation of Necrotizing Fasciitis (NF) is characterized by a constellation of signs and symptoms that reflect the profound tissue destruction and systemic inflammation associated with the disease. Central to its diagnosis is the presence of severe pain that is often disproportionate to the physical findings, serving as a red flag for clinicians to suspect NF.

Visible changes in the skin and soft tissues are hallmark features of NF, including erythema, edema, and swelling over the affected area. These cutaneous manifestations may rapidly progress to necrosis, with the development of dusky discoloration and bullae formation. The affected skin often exhibits tense, shiny, and warm characteristics due to underlying inflammation and tissue edema.

Patients with NF may experience systemic symptoms indicative of severe infection and sepsis, including fever, tachycardia, and hypotension. These systemic manifestations reflect the host’s systemic inflammatory response to the bacterial toxins and cytokines released during the infectious process.

In advanced cases, the presence of gas within the soft tissues may result in subcutaneous crepitus, palpable as a crackling sensation upon palpation. This clinical finding, known as “gas gangrene,” is highly suggestive of NF and mandates urgent intervention.

Furthermore, anesthesia or hypoesthesia over the affected area may occur due to nerve involvement or tissue ischemia secondary to vascular compromise. This loss of sensation, coupled with the intense pain experienced by patients, underscores the severity of NF and underscores the urgency of prompt medical evaluation and intervention.

The signs and symptoms of NF encompass a spectrum of clinical manifestations ranging from localized tissue changes to systemic inflammatory responses. Timely recognition and intervention are essential to prevent disease progression and mitigate the devastating consequences of NF. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

Etiology

The etiology of Necrotizing Fasciitis (NF) is multifactorial, involving a complex interplay between bacterial pathogens, host factors, and environmental influences. Central to its development are the virulent characteristics of the implicated bacterial species, primarily group A Streptococcus (GAS) and Staphylococcus aureus.

These bacteria possess an arsenal of virulence factors, including exotoxins, enzymes, and surface adhesins, which enable them to adhere to and invade host tissues. Once within the host, these pathogens proliferate rapidly, producing toxins that mediate tissue destruction and evade host immune defenses.

Nursing Paper Example on Necrotizing Fasciitis [SOLVED]

Host factors play a critical role in predisposing individuals to NF, with immunocompromised states such as diabetes mellitus, chronic renal failure, or HIV infection increasing susceptibility to infection. Additionally, conditions compromising the integrity of the skin barrier, such as dermatologic conditions or recent trauma/surgery, create portals of entry for bacterial invasion.

Traumatic wounds serve as common entry points for NF-causing pathogens, providing a foothold for bacterial colonization and subsequent tissue invasion. Surgical incisions, particularly in contaminated or poorly perfused areas, can also become sites of infection, especially in the presence of predisposing factors such as diabetes or peripheral vascular disease.

Microbial synergy contributes to the pathogenesis of NF, with polymicrobial infections often observed in affected individuals. The synergistic action of multiple bacterial species potentiates tissue destruction and inflammation, accelerating disease progression.

Environmental factors may also influence the incidence of NF, with warmer climates and aquatic environments favoring the growth of certain bacteria implicated in NF, such as Vibrio species.

The etiology of NF is multifaceted, involving a complex interplay between bacterial virulence factors, host predisposing factors, and environmental influences. Understanding these underlying mechanisms is essential for implementing preventive measures and targeted interventions to mitigate the impact of NF. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

Pathophysiology

The pathophysiology of Necrotizing Fasciitis (NF) revolves around a cascade of events triggered by bacterial invasion and subsequent host immune responses. Upon entry into the host, virulent bacterial pathogens such as group A Streptococcus (GAS) and Staphylococcus aureus proliferate rapidly within the subcutaneous tissues, releasing an array of toxins and enzymes.

These bacterial toxins, including streptococcal pyrogenic exotoxins and staphylococcal exotoxins, initiate an inflammatory response characterized by the release of cytokines and chemokines. This inflammatory milieu attracts immune cells to the site of infection, leading to the recruitment of neutrophils and macrophages in an attempt to eradicate the invading pathogens.

Simultaneously, bacterial enzymes such as hyaluronidase, collagenase, and proteases facilitate tissue destruction by breaking down extracellular matrix components, including collagen and elastin. This enzymatic degradation compromises tissue integrity and disrupts normal tissue architecture, contributing to the rapid spread of infection along fascial planes.

Microvascular thrombosis, induced by bacterial toxins and host inflammatory mediators, further exacerbates tissue ischemia and necrosis. Occlusion of small blood vessels impairs tissue perfusion, leading to hypoxia and subsequent tissue death.

The formation of gas within the soft tissues, known as “gas gangrene,” is a hallmark feature of advanced NF cases. Gas production results from bacterial fermentation of tissue substrates and is facilitated by the presence of anaerobic conditions within the necrotic tissue.

The combination of bacterial toxins, enzymatic degradation, microvascular thrombosis, and tissue ischemia culminates in the characteristic clinical manifestations of NF, including rapidly spreading erythema, edema, and tissue necrosis. Timely recognition of these pathophysiological processes is essential for initiating prompt intervention and preventing further tissue damage and systemic complications associated with NF. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

DSM-5 Diagnosis

The diagnosis of Necrotizing Fasciitis (NF) relies on a combination of clinical findings, laboratory tests, and imaging studies to confirm the presence of the infection and guide appropriate management strategies. While there is no specific diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) for NF, healthcare providers utilize a comprehensive approach to establish the diagnosis.

Clinical evaluation begins with a thorough history and physical examination, focusing on identifying risk factors, assessing the progression of symptoms, and identifying characteristic signs of NF. The presence of severe pain disproportionate to physical findings, rapidly spreading erythema, edema, and tissue necrosis are key clinical features suggestive of NF.

Laboratory investigations play a vital role in supporting the diagnosis of NF, with complete blood count (CBC), inflammatory markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), and blood cultures aiding in the assessment of systemic inflammation and identification of causative pathogens.

Imaging studies, including computed tomography (CT) and magnetic resonance imaging (MRI), are valuable adjuncts in the diagnosis of NF, providing detailed visualization of soft tissue involvement, extent of necrosis, and presence of gas within the affected tissues. Findings such as thickening of fascial planes, fluid collections, and gas tracking along fascial planes are indicative of NF.

Definitive diagnosis often requires surgical exploration and tissue biopsy, with histopathological examination confirming the presence of necrotic tissue and identifying the causative pathogens. Cultures obtained from tissue samples guide antibiotic therapy and help identify polymicrobial infections commonly associated with NF.

The diagnosis of NF is a multifaceted process that encompasses clinical, laboratory, and imaging evaluations. Timely recognition and intervention are paramount for improving patient outcomes and preventing the devastating consequences of this rapidly progressive infection. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

Treatment Regimens and Patient Education

Effective management of Necrotizing Fasciitis (NF) necessitates a multidisciplinary approach, involving early recognition, aggressive surgical intervention, antimicrobial therapy, and comprehensive patient education to optimize outcomes and minimize complications.

Surgical intervention, in the form of extensive surgical debridement, is the cornerstone of NF management. Prompt and thorough removal of necrotic tissue is essential to eliminate the source of infection, reduce bacterial burden, and halt disease progression. Surgical exploration should encompass wide margins beyond the visibly affected tissue to ensure complete removal of infected and necrotic material.

Antimicrobial therapy is initiated empirically upon suspicion of NF and subsequently tailored based on culture and sensitivity results. Broad-spectrum antibiotics targeting common NF pathogens, including group A Streptococcus, Staphylococcus aureus, and anaerobic bacteria, are typically employed. Intravenous administration of antibiotics ensures adequate tissue penetration and systemic coverage to combat the rapidly spreading infection.

Intravenous fluid resuscitation and hemodynamic support are vital components of NF management, aimed at stabilizing patients in the setting of sepsis and systemic inflammatory response syndrome (SIRS). Aggressive fluid resuscitation helps maintain tissue perfusion and organ function, while vasopressors may be required to support blood pressure in cases of septic shock.

Patient education plays a pivotal role in NF management, empowering individuals to recognize early warning signs, adhere to treatment regimens, and adopt preventive measures to reduce the risk of recurrence. Patients and caregivers should be educated about the importance of meticulous wound care, including regular dressing changes and monitoring for signs of infection.

Emphasis should be placed on the significance of seeking immediate medical attention for any signs of infection, such as increasing pain, redness, swelling, or drainage from the wound. Early intervention is paramount in preventing disease progression and minimizing tissue damage.

Furthermore, patients should be educated about the potential complications of NF, including tissue loss, limb amputation, and systemic sequelae such as septic shock and organ failure. Open communication and ongoing support are essential to address patient concerns, promote treatment adherence, and facilitate the recovery process.

The management of NF requires a coordinated approach encompassing surgical intervention, antimicrobial therapy, fluid resuscitation, and patient education. Timely recognition, aggressive treatment, and comprehensive patient engagement are essential to optimize outcomes and mitigate the devastating consequences of this potentially life-threatening infection. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

Conclusion

Necrotizing Fasciitis (NF) stands as a formidable challenge, demanding a comprehensive and multidisciplinary approach for effective management. Through the exploration of its causes, symptoms, etiology, pathophysiology, diagnosis, treatment regimens, and patient education strategies, this paper sheds light on the intricate facets of NF. By dividing the content into concise paragraphs, each focusing on a specific aspect of NF, clarity and readability are enhanced. The use of transition words facilitates the flow of information, guiding the reader through the complexities of NF. Emphasizing patient education underscores the importance of empowering individuals to recognize early warning signs and adhere to treatment regimens, ultimately improving outcomes and reducing morbidity and mortality associated with NF. As we strive to unravel the mysteries of NF and enhance our understanding of this devastating infection, collaboration among healthcare providers, patients, and caregivers remains paramount in the ongoing battle against this relentless adversary. (Nursing Paper Example on Necrotizing Fasciitis [SOLVED])

References

https://www.ncbi.nlm.nih.gov/books/NBK430756/

 
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Nursing Paper Example on Neoplasm [SOLVED]

Nursing Paper Example on Neoplasm [SOLVED]

Neoplasm, commonly referred to as a tumor, embodies an aberrant growth of tissue, presenting a formidable challenge in healthcare due to its potential for benign or malignant outcomes. With its profound impact on patient health and well-being, comprehending the origins, symptoms, and treatment modalities of neoplasms is imperative for medical practitioners and patients alike. This paper aims to provide a thorough examination of neoplasms, delving into their multifaceted causes, diverse symptomatology, and intricate treatment regimens. By elucidating the complexities surrounding neoplastic growth, this discussion seeks to empower healthcare professionals with the knowledge necessary for effective diagnosis and management, while also equipping patients with the understanding needed to navigate their journey towards recovery with confidence and resilience. Through a holistic exploration of neoplasm, we endeavor to shed light on this enigmatic entity, fostering greater awareness and fostering hope for improved outcomes in the battle against cancer. (Nursing Paper Example on Neoplasm [SOLVED])

Nursing Paper Example on Neoplasm [SOLVED]

Causes

Neoplasms arise from a complex interplay of genetic and environmental factors. Genetic mutations, whether inherited or acquired, play a pivotal role in initiating tumorigenesis. These mutations can occur in oncogenes, which promote cell proliferation, or tumor suppressor genes, which inhibit uncontrolled cell growth. Environmental exposures to carcinogens significantly contribute to the development of neoplasms. Carcinogens such as tobacco smoke, ionizing radiation, and certain chemicals found in the workplace or environment can induce DNA damage, leading to oncogenic mutations. Lifestyle factors also influence neoplasm risk, with poor dietary choices, sedentary behavior, and excessive alcohol consumption all implicated in tumorigenesis.

Chronic infections represent another avenue through which neoplasms can emerge. Viral infections, such as those caused by human papillomavirus (HPV), hepatitis B, and hepatitis C viruses, are associated with various cancers, including cervical, liver, and gastric cancers. The persistent inflammation and immune dysregulation triggered by these infections create an environment conducive to tumor formation. Additionally, hormonal factors can influence neoplasm development, with hormonal imbalances or prolonged exposure to estrogen increasing the risk of breast and endometrial cancers.

Moreover, age is a significant risk factor for neoplasms, with the incidence of cancer rising with advancing age due to cumulative exposure to mutagenic insults and the gradual accumulation of genetic alterations. Finally, genetic predispositions inherited from family members can predispose individuals to certain types of neoplasms, highlighting the importance of genetic counseling and screening in high-risk populations. Overall, the causes of neoplasms are multifactorial, encompassing genetic, environmental, lifestyle, infectious, hormonal, and hereditary influences, underscoring the need for comprehensive strategies to mitigate risk and improve early detection and intervention. (Nursing Paper Example on Neoplasm [SOLVED])

Signs and Symptoms

The signs and symptoms of neoplasms can manifest in diverse ways, reflecting the tumor’s location, size, and type. General symptoms often include unexplained weight loss, persistent fatigue, and vague discomfort, which may initially go unnoticed or be attributed to other factors. Localized symptoms depend on the tumor’s specific site, with common manifestations including the presence of palpable masses or lumps, changes in bowel or bladder habits, and persistent pain or discomfort. These symptoms may be indicative of the tumor exerting pressure on surrounding tissues or organs, disrupting their normal function.

Nursing Paper Example on Neoplasm [SOLVED]

Furthermore, neoplasms can elicit systemic symptoms that affect the entire body, such as fever, night sweats, and loss of appetite. These constitutional symptoms often accompany advanced disease and indicate a more aggressive tumor behavior or the presence of metastases. Specific symptoms may also arise based on the tumor’s functional properties or its impact on neighboring structures. For instance, brain tumors can cause headaches, seizures, or neurological deficits, while hormonal tumors may lead to endocrine abnormalities, such as hypersecretion or hyposecretion of hormones.

Moreover, the onset and progression of symptoms vary widely among individuals, with some patients experiencing subtle changes over an extended period, while others may present with sudden, severe symptoms indicative of rapidly advancing disease. Early detection of neoplasms relies on recognizing these signs and symptoms and promptly investigating their underlying cause. Therefore, healthcare providers must maintain a high index of suspicion for neoplastic disease, particularly in patients with risk factors or concerning clinical presentations. By vigilantly monitoring for signs and symptoms suggestive of neoplasms, healthcare professionals can facilitate timely diagnosis and intervention, potentially improving patient outcomes and quality of life. (Nursing Paper Example on Neoplasm [SOLVED])

Etiology

The etiology of neoplasms encompasses a myriad of factors, ranging from genetic predispositions to environmental exposures and lifestyle choices. At the core of neoplastic development lies genetic instability, characterized by mutations in key regulatory genes governing cell growth and proliferation. These genetic alterations can arise spontaneously or be inherited from familial predispositions, predisposing individuals to an increased risk of tumorigenesis. Oncogenes, which promote cell division, and tumor suppressor genes, which inhibit abnormal growth, are frequently implicated in neoplasm pathogenesis. Mutations in these genes disrupt the delicate balance of cellular homeostasis, leading to uncontrolled proliferation and tumor formation.

Furthermore, environmental factors play a significant role in neoplasm etiology, with exposure to carcinogens contributing to DNA damage and oncogenic mutations. Carcinogens such as tobacco smoke, ultraviolet radiation, and certain chemicals found in industrial settings or pollutants can initiate neoplastic transformation by inducing genetic alterations or promoting tumor growth. Lifestyle choices, including diet, physical activity, and substance use, also influence neoplasm risk, with unhealthy behaviors exacerbating the effects of genetic predispositions and environmental exposures.

Additionally, chronic inflammation and immune dysregulation contribute to neoplastic progression by creating a tumor-permissive microenvironment. Inflammatory mediators and cytokines released in response to tissue injury or infection can promote cell proliferation, angiogenesis, and metastasis, fostering a milieu conducive to tumor growth. Infectious agents, such as viruses and bacteria, can also drive neoplastic transformation through direct viral integration into the host genome or by inducing chronic inflammation and tissue damage.

Moreover, hormonal imbalances play a role in neoplasm etiology, with certain tumors exhibiting hormone-dependent growth patterns. Endocrine disruptors and hormonal therapies can influence tumor development by altering hormone levels and signaling pathways. Finally, age and genetic predispositions inherited from family members contribute to neoplasm susceptibility, highlighting the importance of genetic counseling and screening in high-risk populations. Overall, the etiology of neoplasms is multifaceted, encompassing genetic, environmental, lifestyle, inflammatory, infectious, hormonal, and hereditary factors, underscoring the need for comprehensive approaches to neoplasm prevention and management. (Nursing Paper Example on Neoplasm [SOLVED])

Pathophysiology

The pathophysiology of neoplasms revolves around the intricate interplay of cellular abnormalities that disrupt normal physiological processes. Central to neoplastic growth is the dysregulation of cell cycle control mechanisms, driven by genetic mutations and epigenetic alterations. Oncogenes, activated by mutations or overexpression, promote uncontrolled cell proliferation, while tumor suppressor genes, when inactivated or silenced, fail to restrain aberrant growth. These genetic abnormalities disrupt the delicate balance between cell proliferation and apoptosis, leading to the unchecked expansion of malignant cells.

Moreover, neoplastic cells exhibit a repertoire of hallmark traits that distinguish them from their normal counterparts. These include sustained proliferative signaling, evasion of growth suppressors, resistance to cell death, and the ability to invade surrounding tissues and metastasize to distant sites. Dysregulated angiogenesis, the formation of new blood vessels, provides neoplastic cells with oxygen and nutrients essential for their survival and proliferation, facilitating tumor growth and progression.

Furthermore, the tumor microenvironment plays a crucial role in neoplasm pathophysiology, fostering an environment conducive to tumor growth and immune evasion. Stromal cells, extracellular matrix components, and immune cells interact with neoplastic cells to create a supportive niche that sustains tumor growth and metastasis. Immune evasion mechanisms, such as the downregulation of major histocompatibility complex molecules and the expression of immune checkpoint proteins, allow tumors to evade detection and destruction by the immune system, facilitating their survival and progression.

Additionally, genetic heterogeneity within neoplasms contributes to treatment resistance and disease recurrence. Clonal evolution and selection pressures imposed by therapeutic interventions drive the emergence of subpopulations of cells with varying degrees of drug sensitivity, leading to treatment failure and disease relapse. Understanding the complex interplay of cellular and molecular events underlying neoplasm pathophysiology is essential for developing targeted therapies and personalized treatment approaches that effectively eradicate tumors while minimizing toxicity and improving patient outcomes. (Nursing Paper Example on Neoplasm [SOLVED])

DSM-5 Diagnosis

While the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), primarily addresses mental health conditions, it also acknowledges the psychological impact of neoplasms on individuals. A neoplasm diagnosis can elicit a range of emotional responses, including anxiety, depression, and adjustment disorders, which may warrant clinical attention and intervention. Patients grappling with a neoplasm diagnosis often experience profound distress and uncertainty about their prognosis, treatment options, and future well-being.

Anxiety disorders commonly co-occur with neoplastic diseases, with patients expressing heightened worry, fear, and apprehension about their health and mortality. Uncertainty surrounding disease progression, treatment outcomes, and potential complications can exacerbate anxiety symptoms, impacting patients’ quality of life and treatment adherence. Additionally, individuals diagnosed with neoplasms may experience symptoms of depression, including persistent sadness, loss of interest or pleasure in activities, and feelings of hopelessness or worthlessness.

Furthermore, adjustment disorders may arise in response to the stressors associated with a neoplasm diagnosis, such as changes in physical functioning, role disruptions, and existential concerns. Patients may struggle to cope with the emotional and practical challenges posed by their illness, leading to maladaptive coping strategies and psychosocial dysfunction. The DSM-5 provides criteria for diagnosing anxiety disorders, depressive disorders, and adjustment disorders, which are essential for identifying and addressing the psychological needs of patients with neoplasms.

Psychological support and interventions, such as cognitive-behavioral therapy, supportive counseling, and pharmacotherapy, play a crucial role in managing psychiatric symptoms and improving overall well-being. Collaborative care models that integrate mental health services into oncology settings can enhance patients’ access to timely and comprehensive care. By addressing the psychological sequelae of neoplastic diseases, healthcare providers can enhance patients’ resilience, coping skills, and quality of life throughout the cancer continuum. (Nursing Paper Example on Neoplasm [SOLVED])

Treatment Regimens and Patient Education

Effective management of neoplasms requires a multidisciplinary approach tailored to each patient’s unique clinical presentation and treatment goals. Treatment regimens for neoplasms encompass a variety of modalities, including surgery, radiation therapy, chemotherapy, immunotherapy, targeted therapy, and supportive care. The selection of treatment modalities depends on factors such as the tumor type, stage, location, and the patient’s overall health status.

Surgery is often the primary treatment for localized neoplasms, aiming to remove the tumor and surrounding tissues to achieve complete resection while preserving organ function and minimizing morbidity. In some cases, surgery may be curative, particularly for early-stage tumors with favorable prognostic features. However, the feasibility of surgical resection depends on factors such as tumor size, location, and accessibility.

Radiation therapy utilizes high-energy radiation beams to target and destroy cancer cells while sparing adjacent healthy tissues. It may be employed as a standalone treatment or in combination with surgery and/or chemotherapy to achieve local tumor control or alleviate symptoms. Advances in radiation technology, such as intensity-modulated radiation therapy (IMRT) and stereotactic body radiation therapy (SBRT), allow for precise delivery of radiation doses, improving treatment efficacy and minimizing toxicity.

Chemotherapy involves the administration of cytotoxic drugs that target rapidly dividing cancer cells, inhibiting tumor growth and spread. Chemotherapy may be administered orally or intravenously and is often used in combination with other treatment modalities to enhance efficacy. While chemotherapy can be associated with significant side effects, such as nausea, vomiting, hair loss, and immunosuppression, supportive care measures can help mitigate these adverse effects and improve tolerability.

Immunotherapy harnesses the body’s immune system to recognize and destroy cancer cells, offering a promising approach for treating neoplasms resistant to conventional therapies. Immune checkpoint inhibitors, monoclonal antibodies, and adoptive cell therapies are among the immunotherapeutic strategies employed to enhance anti-tumor immune responses and induce durable remissions in select patient populations.

Targeted therapy exploits specific molecular aberrations driving neoplastic growth, allowing for personalized treatment approaches tailored to the tumor’s molecular profile. By targeting key signaling pathways or driver mutations, targeted therapies can selectively inhibit tumor proliferation while sparing normal cells, thereby minimizing toxicity and improving treatment outcomes. Patient education plays a crucial role in empowering individuals to make informed decisions about their treatment options and actively participate in their care. It involves providing comprehensive information about the diagnosis, treatment modalities, potential side effects, and supportive care resources available. Additionally, patients should be educated about the importance of adherence to treatment regimens, symptom management strategies, and the need for regular follow-up appointments to monitor treatment response and address any concerns or complications promptly. Patient education also encompasses discussions about lifestyle modifications, such as dietary changes, exercise regimens, smoking cessation, and stress management techniques, that can optimize treatment outcomes and enhance overall well-being. By fostering open communication, shared decision-making, and patient-centered care, healthcare providers can empower patients to navigate their cancer journey with confidence and resilience, promoting better treatment adherence, quality of life, and long-term outcomes. (Nursing Paper Example on Neoplasm [SOLVED])

Conclusion

Neoplasms present multifaceted challenges in healthcare, necessitating a comprehensive understanding of their causes, symptoms, and treatment modalities. By delving into the complex etiology of neoplasms, we illuminate the interplay of genetic, environmental, and lifestyle factors that contribute to tumorigenesis. Understanding the pathophysiology of neoplastic growth underscores the importance of targeted treatment approaches and personalized interventions to improve patient outcomes. Moreover, recognizing the psychological impact of neoplasms underscores the need for integrated mental health services and patient-centered care models that address the emotional needs of individuals facing a cancer diagnosis. Treatment regimens encompass a diverse array of modalities, including surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, tailored to each patient’s unique clinical presentation and treatment goals. Patient education plays a pivotal role in empowering individuals to make informed decisions about their care, fostering collaboration, and promoting optimal treatment adherence and outcomes. Through ongoing research, education, and collaborative efforts, we strive to advance the field of oncology and improve the lives of individuals affected by neoplasms. (Nursing Paper Example on Neoplasm [SOLVED])

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150252/

 
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Leadership Theories Comparison Chart

Leadership Theories Comparison Chart

(Leadership Theories Comparison Chart)

Leadership Theories Comparison Chart

Leadership Theory How Theory Supports Organizational Change
Transformational Leadership Theory:

The transformational leadership theory was established in the 1970s by James McGregor Burns. According to the transformational leadership theory, a leader’s vision can inspire a whole team to achieve feats they never imagined possible (Steinmann et al., 2018). As a result, the group members are more inclined to have faith in this visionary who so greatly motivates them. It is frequently applied to staff motivation and general leadership style assessment. Because these leaders are skilled at resolving conflicts, they encourage and drive their teams to find better ways to accomplish a goal (Steinmann et al., 2018). They can organize people into productive groups, improving the group’s well-being, morale, and motivation using strong rapport. Key elements of transformational leadership include individualized consideration, intellectual stimulation, inspirational motivation, and idealized influence. (Leadership Theories Comparison Chart)

 

More people must act as transformational leaders for organizations to adapt successfully to change. Successful transformational leaders can alter a company’s culture and create a system-wide synchronization of its strategy to respond to external pressures. Transformational leadership affects both social systems and individual behavior during organizational change (Steinmann et al., 2018). In its optimal state, it brings about significant and constructive change in the employees with the ultimate objective of transforming them into leaders. When practiced in its purest form, transformational leadership improves people’s motivation, morale, and output via several processes like encouraging employees to take increased responsibility for their work, challenging them to do so, and recognizing and understanding the strengths and weaknesses of employees so the leader can assign them to tasks that maximize their performance, and linking an individual’s sense of identity and self to the organization’s mission and shared identity (Steinmann et al., 2018). Conclusively, transformational leaders allow employees to own and identify with the change and actually be leaders in the change process.      (Leadership Theories Comparison Chart)
Transactional Leadership Theory:

This leadership theory examines how leaders deal with their staff members. Transactional leaders want their subordinates to abide by their rules. In contrast, the expectations of transformational leaders are higher than those of ordinary leaders. As a result, this concept is frequently applied to people who have little expertise in leadership and who require step-by-step guidance on how to carry out responsibilities efficiently (Richards, 2020).

The premise of the transactional leadership theory is that managers should provide people with what they desire in exchange for cooperation. It asserts that employees need structure, guidance, and supervision to execute jobs correctly and on time because they lack self-motivation (Richards, 2020). After World War II, the transactional leadership style became quite popular in the US. A high level of organization was needed to sustain national stability during this period of government focus on reconstruction. Contingent reward, which entails the establishment of expectations and rewarding employees for achieving them; passive management by exception, in which a leader does not intrude with workflow until a problem occurs; and active management by exception, where leaders foresee issues, track progress, and provide remedial action, are some of the facets of transactional leadership (Richards, 2020). (Leadership Theories Comparison Chart)

Transactional leaders operate in line with specified operating procedures. They are more focused on maintaining continuity in day-to-day operations, ensuring everything runs smoothly by putting systems and processes in place and concentrating on achieving goals (Richards, 2020). Such leaders can impose punitive measures, create a systematic framework, specify a course of action, develop and carry out policies, and encourage exceptional performance through rewards and incentives. A transactional leader is more interested in ensuring that the planned activities are accomplished on time and to the highest standard than. However, transactional leaders lack a futuristic vision or tactics for gaining market leadership. With this understanding, transactional leaders are more suited to developing and influencing short-term changes or changes in the daily procedures and processes to make task completion more efficient and successful (Richards, 2020). (Leadership Theories Comparison Chart)
Servant Leadership Theory:

According to the philosophy of servant leadership, a leader should set their own needs aside to support others’ development and growth (Allen et al., 2018). It is what they meant when they said, “It is not about me; it is about the patient,” at any time. Putting patients first is the key goal in this theory in healthcare, which is a commendable trait for any leader. Servant leadership suggests that a leader genuinely cares about giving each team member the support and resources they require to be successful. Servant leadership can be incredibly helpful when managing a diversified, varied team. Regardless of the positions, skills, or resource needs of any team member, servant leaders are exceptional at satisfying individual team members’ needs. Servant leadership adopts a holistic approach and wider emphasis on affecting other people and team-level performance like change ownership behavior, job performance, job satisfaction, and organizational commitment and loyalty compared to other theories, which makes it the most promising and explored concept recently (Allen et al., 2018). (Leadership Theories Comparison Chart)

Servant leaders are considered change agents in organizations, empowering employees to take more responsibility toward organizational change. Servant leaders share visions with employees and lead from behind, supporting individual development in the organization to take more ownership in the change implementation. Servant leaders are also more effective in influencing people and convincing people of the need for change because they instill trust in employees, who, in turn, invest more commitment and energy toward organizational change and achieving desired goals and results (Zhou et al., 2022).

According to Warren Bennis, organization development is a sophisticated approach designed to alter organizations’ attitudes, values, and organizational structure to improve their capacity to respond to emerging markets, technologies, and problems. The leader must therefore be aware of the pulse of their workforce in light of the rapidly and always changing environment and aid in transforming their organizations into vital and successful entities through change initiation and adoption (Allen et al., 2018). A leader who genuinely wants to comprehend others will only be able to determine what direction the organization and individual employees have to move to accomplish desired goals. The demand for servant leaders whose decision-making is comprehensive and who support organizations in thriving has never been greater than it is today. (Leadership Theories Comparison Chart)

References

Allen, G. P., Moore, W. M., Moser, L. R., Neill, K. K., Sambamoorthi, U., & Bell, H. S. (2018). The Role of Servant Leadership and Transformational Leadership in Academic Pharmacy. American journal of pharmaceutical education80(7), 113. https://doi.org/10.5688/ajpe807113

Richards A. (2020). Exploring the benefits and limitations of transactional leadership in healthcare. Nursing standard (Royal College of Nursing (Great Britain) : 1987)35(12), 46–50. https://doi.org/10.7748/ns.2020.e11593

Steinmann, B., Klug, H. J. P., & Maier, G. W. (2018). The Path Is the Goal: How Transformational Leaders Enhance Followers’ Job Attitudes and Proactive Behavior. Frontiers in psychology9, 2338. https://doi.org/10.3389/fpsyg.2018.02338

Zhou, G., Gul, R., & Tufail, M. (2022). Does Servant Leadership Stimulate Work Engagement? The Moderating Role of Trust in the Leader. Frontiers in psychology13, 925732. https://doi.org/10.3389/fpsyg.2022.925732

 
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NSG 301 Thesis Worksheet

NSG 301 Thesis Worksheet

(NSG 301 Thesis Worksheet)

Name:

Instructions: Please write your answers directly into this document and do not delete the questions or instructions. I have highlighted wherever a response is required. You may wish to use a different font, text color, or boldface to make your answers more visible, although it’s not required. When completed, “Save as” and add your last name to the file name. (NSG 301 Thesis Worksheet)

 

GATHERING THE PIECES

 

Go back to your Problem Statement Worksheet in LM3. Copy and paste the problem statement (the answer to L, the last question on that worksheet) here.

 

Problem Statement: Poor health-promoting self-care behavior impacts nurses’ health and well-being, contributing to overweight and obesity and mental health issues. (NSG 301 Thesis Worksheet)

NSG 301 Thesis Worksheet

 

I still stand by this statement that “Poor health-promoting self-care behavior impacts nurses health and well-being, contributing to overweight and obesity and mental health issues.” I have searched multiple databases and organizational publications such as the CDC, ANA, and other healthcare organization that offer statistical evidence and found concrete and valid evidence supporting the claim. However, most sources are also addressing root causes, and therefore, I decided to adjust the problem statement to include some of the identified root causes contributing to medication errors. The new statement reads, “Work related factors, including work-related stress, heavy workloads, shift work, poor engagement and communication, increasing patient health demands, and working overtime lead to poor health-promoting self-care behavior that impacts nurses health and well-being, contributing to overweight and obesity and mental health issues.” (NSG 301 Thesis Worksheet)

 

Now that you’ve done some research, do you still stand behind this statement? Did you find evidence to support the claim? If not, make a new supportable claim about the same problem below. (If you changed topics since the Problem Statement Worksheet, give your new problem statement below.) Remember, short and simple is best!

For example, I made the claim “Excessive wait times in the ED increase the likelihood that patients will become violent.” Let’s assume that I didn’t find any solid evidence of a causal relationship between wait times and patient violence in the ED, but I did find statistics showing that violence occurs more often in the EDs than any other healthcare setting. I see two possibilities for revision of this claim: 1. I could simplify the claim to remove the cause (e.g., “Violence is more common in the ED than in other healthcare settings.”), or 2. I could claim that wait times in the ED have some other bad effects worth avoiding (e.g., “Excessive wait times in the ED lower patient satisfaction.”), depending on what I discovered in my research and whether I am more interested in pursuing solutions that reduce violence or ones that reduce wait times. (NSG 301 Thesis Worksheet)

 

Revised Problem Statement (if needed): Work related factors, including work-related stress, heavy workloads, shift work, poor engagement and communication, increasing patient health demands, and working overtime lead to poor health-promoting self-care behavior that impacts nurses health and well-being, contributing to overweight and obesity and mental health issues.

 

 

Now let’s think about outcomes and solutions. Your Summary Table and any other research you’ve done will help you to complete these lists. Any intervention studies you’ve read will include specific actions taken (interventions) and results that were measured (outcomes) so list those! You shouldn’t need to make any of these up from scratch. (NSG 301 Thesis Worksheet)

 

Examples of MEASURABLE outcomes
Increased satisfaction scores (Be specific: nurse job satisfaction, patient satisfaction, family satisfaction, provider satisfaction, etc. Each of these must be measured independently of the others and so are separate outcomes.)
Conserve a finite resource (Be specific: money, time, vehicle mileage, PPE, etc. Each of these must be measured independently of the others and so are separate outcomes.)
Reduced rates of something bad (such as falls, infections, sentinel events, mortality rates, etc. Each would need to be listed separately.)
Increased rates of something good (such as compliance with a policy, medication compliance, compassion satisfaction, etc. Each would need to be listed separately.)
Some outcomes are related! For exact opposites (e.g., decreased mortality and increased survival) use one, not both. Be careful with closely related outcomes, especially decreased turnover, increased retention, reduced intention to leave, reduced burnout, increased compassion satisfaction, reduced compassion fatigue! These are all related but NOT interchangeable! (Be specific. If more than one applies, list each separately.)
Too vague! Don’t use!
Improved outcomes
Happier nurses (or patients or whoever); Better experience
Address the problem

 

 

Examples of interventions
Training in a specific skill (manager training in X leadership style, online course for nurses on X, interdisciplinary workshop of X skill, etc. Be specific! You may include more than one specific training, but list them separately.)
A particular process change (moving handoff report to bedside, using a new cleanser for catheter insertion sites, add a particular checklist to the EMR, a specific kind of rounding, etc. Be specific! You may include more than one specific process change, but list them separately.)
A specific change to policy (new open bed alert system, longevity incentive pay, maximum patient:nurse ratios, etc.)
Any concrete, recommended action (purchase a new kind of monitor system, enforce an existing policy, hire for a particular role, install massage chairs in the break room, etc.)
Too vague! Don’t use!
Implement solutions
Address the problem
Improve X (Anything you want to improve, increase, or decrease is probably an outcome, not an action.)

 

For the two lists below, come up with at least 1 answer for each list. You should have at least 3 answers in ONE of the lists.

 

List positive MEASURABLE outcomes you would like to achieve in order to mitigate the problem: (There are many ways to measure outcomes. For instance, you might measure “reduced stress” through a pre-/post-intervention survey or by taking subjects’ BP and pulse. For this list, indicate outcomes which are possible to measure, not the methods of measurement.) Put only one outcome on each line. You may add as many lines as you need to.

 

  1. Improved nurses’ health and well-being.
  2. Reduced work-related factors contributing to poor health-promoting self-care behavior.
  3. Improved healthcare quality, patient safety, and patient outcomes.

 

List some of the interventions that have been studied as potential solutions to your problem: Keep in mind that an intervention is a specific solution action, not just a reversal of the problem. Think of each action as a command that someone has to carry out. “Go enforce nurse autonomy!” would be far too open-ended, but “Train providers to respect the scope of nursing practice!” conveys what should be done. Put only one solution action/intervention on each line. You may add as many lines as you need to.

 

  1. Improve the working environment to be more engaging and coordinated, less stressful, and have manageable workloads: (nurse leaders and nurse staff) A, B, C.
  2. Adopt self-care strategies such as emotional regulation, self-compassion, mindfulness, healthy eating patterns, regular physical activity, staying connected, and continued individual and professional growth to minimize adverse effects of poor health promoting behavior. (nurses). A, C.
  3. Provide stress management workshops and self-care education sessions during lunch and off-work periods (Hospital administration, nurses, and nurse leaders) A, C.

 

Look at each of your interventions and decide WHO would have the power to make that change happen. Some changes nurses can make themselves, such as adopting bedside handoff or meditating to relieve stress. Other changes require management to get involved, such as adopting or enforcing a bedside handoff policy or bringing in a meditation instructor to offer training. Some changes can only be done by hospital or system administrators, such as adopting a patient:nurse ratio policy or adding incentive pay. In the INTERVENTION list above, next to each intervention, write the appropriate audience in parentheses. If more than one could apply, feel free to indicate that. Ultimately, you will pick just ONE audience capable of the entire proposal, whether it has just one recommended action or three. (NSG 301 Thesis Worksheet)

 

Match up each intervention with the measurable outcomes associated with it, as shown in the literature. You’ve got a list of interventions with a number assigned to each. You’ve got a list of outcomes with a letter assigned to each. In the list of interventions, after the audience, write the letters for ALL the outcomes that come from doing that action.

For example, if my outcome list looks like this:

  1. New nurse retention
  2. New nurse competency
  3. New nurse satisfaction

My intervention list might look like this, once completed:

  1. Nurse residency program (management) A, B, C
  2. Mentorship (management) A, C
  3. Civility training for all staff (management) C

This indicates that I found correlations in the literature between NRPs and all 3 outcomes, between mentorship and both retention and satisfaction of new nurses, and between staff civility training and new nurse satisfaction.

(NSG 301 Thesis Worksheet)

 

 

For this paper, you want to have a 3-part thesis. You may choose 3 interventions which all have the same outcome OR 1 intervention that has 3 distinct outcomes. Which you choose depends on your research; pick the option that lets you use the best of the studies you already have. It’s also OK if you discover that you’ll need to do more research to connect all the pieces you want to include. Pay attention to the audiences you have for each intervention! You should write for only one audience

In my example, there are 2 obvious choices: I could choose 1 intervention (NRP) and 3 outcomes (retention, competency, and satisfaction), or I could choose to write about all 3 interventions, but focus only on how each of them increases the same shared outcome (satisfaction). But I do have other options! Maybe I’m really passionate about retention, and I’d rather write about 3 interventions (NRPs, mentorship, and another TBD by further research) focused on that 1 outcome (retention).

 

Write your choices below. Keep in mind that if you have 3 interventions, you must have only 1 outcome; if you have only 1 intervention, you must have 3 outcomes. You may use up to 1 “placeholder” (such as TBD) that indicates a need to do more research. (NSG 301 Thesis Worksheet)

 

My audience: Nurses

My intervention(s):

  1. Improve the working environment to be more engaging and coordinated, less stressful, and have manageable workloads.
  2. Adopt self-care strategies such as emotional regulation, self-compassion, mindfulness, healthy eating patterns, regular physical activity, staying connected, and continued individual and professional growth to minimize adverse effects of poor health promoting behavior.
  3. Provide stress management workshops and self-care education sessions during lunch and off-work periods.

My outcomes(s): Improved nurses’ health and well-being.

 

WRITE YOUR DRAFT/WORKING THESIS STATEMENT

Use one of the templates below to draft your working thesis statement. (“Working” just means that it may still change.) Make sure your thesis statement is a single sentence and grammatically correct. You might need to add some verbs to your interventions (create, implement, enforce, adopt) and outcomes (increase, decrease, improve). Use punctuation, check your spelling, proofread.

 

3 Actions, 1 Outcome:

Since    [Problem Statement]   ,    [audience]    should    [1st intervention], [2nd intervention], and [3rd intervention]   , in order to    [1 positive outcome]   .

 

OR

 

1 Action, 3 Outcomes:

Since    [Problem Statement]   ,    [audience]    should    [1 intervention]    in order to    [1st positive outcome], [2nd positive outcome], and [3rd positive outcome]   .

 

My working thesis statement:

Since work-related factors, including work-related stress, heavy workloads, shift work, poor engagement and communication, increasing patient health demands, and working overtime lead to poor health-promoting self-care behavior that impacts nurses health and well-being, contributing to overweight, obesity, and mental health issues, nurses should improve the working environment to be more engaging and coordinated, less stressful, and have manageable workloads, adopt self-care strategies such as emotional regulation, self-compassion, mindfulness, healthy eating patterns, regular physical activity, staying connected, and continued individual and professional growth, and provide stress management workshops and self-care education sessions during lunch and off-work periods to improve nurses’ health and well-being. (NSG 301 Thesis Worksheet)

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761038/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832775/

https://pubmed.ncbi.nlm.nih.gov/2665107/

 
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Benchmark – Human Experience Across the Health-Illness Continuum

Benchmark – Human Experience Across the Health-Illness Continuum

 (Benchmark – Human Experience Across the Health-Illness Continuum)

Benchmark - Human Experience Across the Health-Illness Continuum

Introduction

An individual’s health state changes continually across the various stages of the health-illness continuum. Individuals move back and forth between illness and health, and it is rare to find an individual in a constant state of either illness or health. The health-illness continuum depicts this process of continual change, in which people experience different states of health and illness, extending from extremely good health to death. Individuals are expected to adapt to the changes in health and learn from states of illness to maintain good health and well-being. Noticeably, people’s adaptation to the changes rather than the change in the state itself impacts their health. A state of wellness is a successful adaptation and effective functioning, even for those experiencing chronic diseases. (Benchmark – Human Experience Across the Health-Illness Continuum)

The Health-Illness Continuum

Nurses adopt the health or illness-wellness continuum to educate patients, demonstrating associations between treatment and wellness elements. The continuum illustrates the path or approaches to a better, healthier life. By incorporating mental and emotional health, this tool shows that well-being is more than merely an absence of a disease or illness. The associations between treatment and wellness paradigms meet at a neutral point on the health-illness continuum diagram (Kishan, 2020). The far left of the diagram represents pre-mature death, and as a person moves from the left, they come to a neutral point, leaving the treatment process and moving into wellness, where high-level wellness is at the far right. This perspective is a fundamental consideration when caring for patients because it allows providers to elaborate on their journey to better health and educate on what should be done to create and maintain a healthy lifestyle and achieve optimal health (Lothes II, 2020). The continuum stresses the need for providers to educate and help patients move further to the left toward high-level wellness.  (Benchmark – Human Experience Across the Health-Illness Continuum)

Benchmark - Human Experience Across the Health-Illness Continuum

The Health-Illness Continuum’s Consistence with the Christian Worldview

In most instances, the typical health system ends at the neutral point, where patients have completed the treatment process and are discharged or achieved a healthy state. However, according to the health-illness continuum, the neutral point is not the endpoint, and healthcare providers should strive to increase awareness, educate patients, and encourage growth toward high-level wellness or optimal health (Wickramarathne et al., 2020). Helping people live a better, healthier life and achieve optimal health income promotes their value and dignity because, according to the Christian Worldview, healthcare providers are caring elements that should demonstrate love and compassion (Ramírez Jiménez & Serra Desfilis, 2020). Offering healthcare reflects the love of God, and adopting the health-illness continuum facilitates efforts to alleviate human suffering, cure disease, grow knowledge through patient education, and extend care beyond illness states. This continuum encourages providers to help patients achieve positive changes in their lifestyle to move to the right of the continuum and live better, healthier lives. (Benchmark – Human Experience Across the Health-Illness Continuum)

Reflection

My overall health is good as I aspire and strive to achieve high-level wellness and live a healthier life. I understand that maintaining optimal health is a personal responsibility, and I fulfill this responsibility by maintaining a healthy diet, engaging in regular physical activity, getting physical examinations regularly, avoiding substance abuse, tobacco, and heavy alcohol consumption, monitoring my body mass index, blood pressure, cholesterol level, and blood glucose level. However, I have not achieved high-level wellness, implying that I need to improve and change some behavior that detracts me from health and well-being, including excessive social media consumption, slacking on sleep, and engaging in negative thinking patterns. Generally, my physical health is good, but I need to improve my mental health to achieve high-level wellness. I fall in the growth state on the health-illness continuum, moving towards high-level wellness. (Benchmark – Human Experience Across the Health-Illness Continuum)

Options and Resources to help achieve High-level Wellness

The greatest resource available to help me move towards wellness includes my nursing knowledge. I have an in-depth understanding of health and well-being, factors affecting health and well-being, behaviors, tools, and options to achieve high-level wellness. Besides sharing this knowledge with patients, I also incorporate it in promoting my health and well-being. Other resources include colleagues at the workplace and family and friends. I can inquire about my health and well-being from my colleagues, who also have comprehensive knowledge about the body and how to achieve optimal health. Friends and family offer social and emotional support on this path to achieving high-level wellness, and I trust them to offer help when I need it. I also have facilities like the community gym, grocery stores selling organic food, my therapist helping with mental health, and infrastructures like bicycle pathways and running trucks to help achieve the optimal physical activity. (Benchmark – Human Experience Across the Health-Illness Continuum)

Conclusion

The health-illness continuum is a graphical tool suitable for healthcare practice, particularly patient education, indicating where an individual is across the various states of health and illness. Individuals can also adopt the tool to guide their path toward better, healthier lives. It offers insights into what point of health or illness an individual is in and prompts decisions regarding behavioral changes to achieve optimal health outcomes. Resources and options to promote wellness are multiple, from our knowledge, people around us, evidence-based publications on the internet, infrastructure like gyms and public parks, and the availability of grocery stores that sell healthy, organic foods. (Benchmark – Human Experience Across the Health-Illness Continuum)

References

Kishan P. (2020). Yoga and Spirituality in Mental Health: Illness to Wellness. Indian journal of psychological medicine42(5), 411–420. https://doi.org/10.1177/0253717620946995

Lothes II, J. (2020). Teaching wellness in a college physical education course: Pre/post outcomes over the semester. Building Healthy Academic Communities Journal4(1), 28-47.

Ramírez Jiménez, M. S., & Serra Desfilis, E. (2020). Does Christian Spirituality Enhance Psychological Interventions on Forgiveness, Gratitude, and the Meaning of Life? A Quasi-Experimental Intervention with the Elderly and Youth. Nursing reports (Pavia, Italy)10(2), 182–206. https://doi.org/10.3390/nursrep10020022

Wickramarathne, P. C., Phuoc, J. C., & Albattat, A. R. S. (2020). A review of Wellness Dimension models: For the advancement of the Society. European Journal of Social Sciences Studies.

 
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Week 6 Final DNP Project Manuscript

Week 6 Final DNP Project Manuscript

(Week 6 Final DNP Project Manuscript)

Methodology

This section describes organizational setting, project population translation science model and project management, plans for sustainability, and anticipated outcomes.

Week 6 Final DNP Project Manuscript

Organizational Setting

The healthcare setting is a general mental health facility for treating various mental health disorders. The organization adopts mental health teams based in communities, especially for schizophrenia patients, that offer daily support and treatment while helping schizophrenia patients gain as much independence as possible. Mental health teams based in communities are more suitable for the patient population because most schizophrenia patients live with their families. The teams include nurses, therapists, psychiatrists, psychologists, and social workers. The healthcare organization is located in Los Angeles, California. The healthcare organization is located in Los Angeles, California.

The study focuses on schizophrenia patients with schizophrenia as the primary diagnosis. Schizophrenia is associated with significant thinking or cognitive, behavioral, and emotional problems. Individuals between the ages of 16 and 25 years are the most vulnerable, although new schizophrenia cases begin increasing in their teenage years. Most patients present with hallucinations, delusions, and confused or disturbed thoughts that impact behavior and social and occupational functioning. About 150-230 schizophrenia patients are seen each month either at the facility or in their respective homes by the mental health teams based in the communities. On average, a hospitalized schizophrenia patient can stay in the hospital for days, ranging between 11 days to 23 days, depending on the condition and symptoms severity. A full-team approach is adopted in addressing schizophrenia at the healthcare organization. A combination of psychopharmacologists, therapists, social workers, nurses, vocational counselors, and case managers contributes to patient health management and outcome. The psychiatrist experienced or specialized in treating schizophrenia guides disease treatment and management, supported by other members of the treatment team that help coordinate care. (Week 6 Final DNP Project Manuscript)

Population

The project population typically includes schizophrenia patients experiencing thinking or cognitive, behavioral, and emotional problems. The patient population consists of both men and women reporting at the facility or requesting home visits from the mental health team based in the communities. The study will include 50 consecutive schizophrenia patients following up with treatment at the facility or home. The inclusion criteria required patients diagnosed with schizophrenia according to the International Statistical Classification of Diseases-10 criteria, patients aged between 18 and 65 years, patients receiving treatment for the last 6 months, follow-up patients, patients with multiple schizophrenia episodes, and patients with recent psychotic relapse after nonadherence to treatment. The exclusion criteria include acutely psychotic patients during the interview and patients with cognitive deficits impacting the interview or data collection. Existing users of health services at the facility will be requested to participate in the study. Informed consent will be required to collect data on the participants. Any follow-up schizophrenia patient attending psychiatric evaluation in the inpatient or outpatient departments will be recruited for the study after consent. The first 50 consecutive schizophrenia patients that fit the inclusion criteria will be involved in the study. Participation requests and details of the study will first be communicated via text messages, which are suitable even for older patients. (Week 6 Final DNP Project Manuscript)

Translational Science Model and Project Management Plan

The Iowa model of evidence-based practice will help implement motivational interviewing to enhance medication adherence among schizophrenia patients. It supports evidence-based practice implementation, research utilization, and knowledge transformation processes (Duff et al., 2020). The Iowa model offers a systematic approach to synthesizing knowledge and research findings transformation to enhance patient outcomes and quality of care. The primary purpose of this model is to increase research findings’ meaningfulness and utility in clinical decision-making (Iowa Model Collaborative et al., 2017). The Iowa model is an application-oriented EBP process guide with the following primary steps:

  1. Identifying either a knowledge-focused or problem-focused trigger that warrants EBP adoption.
  2. Determining if the identifying problem is a priority for the institution, practice, department, or clinical setting (Cabarrus College of Health Sciences, 2023).
  3. Establishing a team to develop, examine, and implement the required EBP change. This must be representative and interdisciplinary to evaluate and adopt the EBP change better.
  4. Gathering and analyzing evidence related to the identified change, including developing the research question and performing a literature search using identified keywords.
  5. Critiquing and synthesizing the collected research evidence to determine whether the EBP change is scientifically supported, sound, and clinically significant.
  6. Assessing whether the evidence is sufficient to implement the EBP change.
  7. Implementing the EBP change into a pilot program rather than a full practice change, for instance, implementing the change in a single nursing unit rather than the entire organization.
  8. Evaluating outcomes or results to determine whether the change achieves its objectives, is feasible, and if it is appropriate to adopt it within the organization. Implementation results’ observation, evaluation, and analysis should continue even after full-practice implementation (Cabarrus College of Health Sciences, 2023).

Per the Iowa model, the DNP practice project development and implementation includes the following steps:

  1. I identified medication non-adherence among schizophrenia patients as warranting EBP adoption.
  2. Medication non-adherence is a priority for the organization as it is linked with increased treatment failure, hospitalization, readmission, and mortality rates. Addressing this problem would improve hospital and patient health outcomes.
  3. I developed a team comprised of a combination of psychopharmacologists, therapists, social workers, nurses, vocational counselors, and case managers to develop, examine, and implement motivational interviewing to address medication non-adherence among schizophrenia patients.
  4. I developed a practice question “For adults with a history of Schizophrenia (P) in the inpatient setting, does the implementation of technology with motivational interviewing (I), compared with current practice (C), impact medication nonadherence (O) in 8-10 weeks (T)?” to guide literature search and the DNP project. I searched for peer-reviewed articles from various databases, including PubMed, MEDLINE, and CINAHL, addressing the impact of motivational interviewing on medication adherence.
  5. I reviewed the articles based on their abstract, research purpose, methodology, research findings, evidence level and quality and presented results of 10 articles on the evidence synthesis summary tool/table. Based on the evidence, motivational interviewing is scientifically supported, sound, and clinically significant.
  6. Ten articles were identified as providing the best evidence to help answer the research question. Based on the assessment, the evidence is sufficient to guide and inform the implementation of motivational interviewing at the healthcare facility.
  7. The project team and I will implement motivation interviewing into a pilot program that include follow-up schizophrenia patients only.
  8. The team and I will evaluate the implementation results to determine the impact of motivational interviewing on medication adherence among schizophrenia patients. Clinically significant results will warrant the implementation of motivational interviewing organization-wide. (Week 6 Final DNP Project Manuscript)

Project Management Plan

The DNP project implementation will take 12 weeks to complete. Week 1 will involve identifying participants and collecting pre-implementation data. In week 2, steps 1, 2, and 3 will be completed, which include problem identification, determination of priority, and team development. In week 3, steps 4, 5, and 5, involving evidence gathering and analysis, research articles critiquing and synthesis, and evidence assessment for adequacy will be completed. The implementation of motivational interviewing will begin in week 4 and through weeks 5, 6, 7, 8, 9, 10, and 11. In week 12, post-summative data after intervention implementation will be collected and outcomes evaluated, which is step 8 of the project implementation plan, to determine the effectiveness of motivational interviewing in addressing medication adherence among schizophrenia patients and whether it is suitable to implement in the rest of the organization and patient populations. (Week 6 Final DNP Project Manuscript)

Table 1: Implementation Plan

Week Activity
Week 1 Pre-implementation data collection.
Week 2 Step 1: Problem identification

Step 2: Determining whether the problem is priority to the organization

Step 3: Team development

Week 3 Step 3: Evidence gathering and analysis

Step 4: Research articles critique and synthesis

Step 5: Evidence assessment for adequacy

Week 4 Step 7: Intervention implementation
Week 5 Step 7: Intervention implementation
Week 6 Step 7: Intervention implementation
Week 7 Step 7: Intervention implementation
Week 8 Step 7: Intervention implementation
Week 9 Step 7: Intervention implementation
Week 10 Step 7: Intervention implementation
Week 11 Step 7: Intervention implementation
Week 12 Post-summative data collection

Step 8: Outcome evaluation

Formative Evaluation Plan

The formative evaluation will include individual evaluation conducted before, during, and after intervention implementation aiming to improve project development and implementation design and performance and ensure activities are completed effectively and efficiently. This formative evaluation will help understand why and how the project works and other factors at work during project development and implementation. This evaluation plan will increase the likelihood of attaining successful results or outcomes through continuous improvements informed by evaluation results at different project implementation steps. (Week 6 Final DNP Project Manuscript)

Table 2: Formative Evaluation Plan

Week When Why How (Oversight)
Week 1 Pre-project implementation ·         Understand the need for the project ·         Leadership meetings
Week 2 Project development ·         Clarify the need for the project ·         Problem tree analysis

·         Priority Matrix

·         Stakeholder analysis

Week 3 Project development ·         Clarify the need for the problem

·         Identify problem impact

·         Clarify intervention selected

·         Literature review

·         Solution tree analysis

Week 4 Project implementation ·         Develop project design before roll-out ·         Focus group

·         Discussions

Week 5 Project implementation ·         Improve project design as it is rolled out ·         Semi-structured interview

·         ORID

·         Project diary

Week 6 Project implementation ·         Ensure project implementation activities are delivered efficiently and effectively. ·         Schedule tracking

·         Budget tracking

·         Observation

·         Dartboard

·         Questionnaire

·         Huddles

Week 7 Project implementation ·         Ensure project implementation activities are delivered efficiently and effectively. ·         Schedule tracking

·         Budget tracking

·         Observation

·         Dartboard

·         Questionnaire

·         Huddles

Week 8 Project implementation ·         Ensure project implementation activities are delivered efficiently and effectively. ·         Schedule tracking

·         Budget tracking

·         Observation

·         Dartboard

·         Questionnaire

·         Huddles

Week 9 Project implementation ·         Ensure project implementation activities are delivered efficiently and effectively. ·         Schedule tracking

·         Budget tracking

·         Observation

·         Dartboard

·         Questionnaire

·         Huddles

Week 10 Project implementation ·         Ensure project implementation activities are delivered efficiently and effectively. ·         Schedule tracking

·         Budget tracking

·         Observation

·         Dartboard

·         Questionnaire

·         Huddles and meetings

Week 11 Project implementation ·         Ensure project implementation activities are delivered efficiently and effectively. ·         Schedule tracking

·         Budget tracking

·         Observation

·         Dartboard

·         Questionnaire

·         Huddles and discussions

Week 12 Post-project implementation ·         Ensure project is completed successfully. ·         Leadership meetings

·         Project team discussions

·         Schedule tracking

·         Budget tracking

·         Observation

·         Dartboard

·         Questionnaire

 

Plans for Sustainability

The sustainability objective is to ensure motivational interviewing is adopted organization-wide and the organization continues to enjoy its benefits in improving medication adherence over time. The sustainability plan will ensure the sustainability objective is achieved. Continuous quality and performance improvement is a post-implementation objective to help ensure the project’s sustainability. First, critical success factors will be developed, including medication adherence measures that will help assess the continued effectiveness of the intervention. Critical success factors include a substantial decrease in treatment failure, hospitalization, readmission, and mortality rates among schizophrenia patients. Consistent improvement of medication adherence and persistent behavior, including patient motivation, self-efficacy, and change and sustain talk, are critical success factors that will also help determine sustainability.

Data collection, observation, and analysis will allow the organization to measure the continual effectiveness of the intervention. Patient records and the organization’s medical data will provide information regarding treatment failure, hospitalization, readmission, and mortality rates over time. Self-reported surveys and interviews will help gather qualitative data to determine changes in medication adherence behavior over time. Project auditing and feedback collection from various stakeholders will also offer insights into the performance of the intervention after implementation and over time. The team selected for patients’ health management and outcome, patients, leaders, and observers will offer feedback regarding the project to help with continuous improvement. Opinion leaders’ involvement and evaluation will help improve the intervention and ensure sustainability. Opinion leaders include external and internal experts, educators, and organizations that advocate for the project; their insights will be critical. The data from these data and insight sources will inform sustainability strategies for continuous quality improvement. Additionally, continuous quality and performance improvement and suitability over time will be achieved through continuous patient and provider education on motivational interviewing and medication management and summative evaluation of education outcomes. Ongoing provider and patient education will help ensure the sustainability of project benefits over time. (Week 6 Final DNP Project Manuscript)

Anticipated Outcomes

Relationship between Motivational Interviewing and Medication Adherence

The primary purpose of motivational interviewing is to enhance medication adherence among schizophrenia patients. Motivation interviewing and medication adherence have a direct relationship, which involves one value directly affecting another, such as variables increasing and decreasing together. In this case, motivational interviewing has no values that increase or decrease, and the presence or absence of it will be analyzed in this paper. Data will be collected for medication adherence measures, which include treatment failure rate, readmission rates, hospitalization rates, and mortality rates, before implementing motivational interviewing and after the implementation. The expectation is a direct causal relationship such that when motivational interviewing is implemented, medication adherence behavior, which will be measured using the indicated medication adherence measures. This direct causal relationship is described as “the implementation of motivational interviewing improved medication adherence” or “motivational interviewing was positively associated with medication adherence.” (Week 6 Final DNP Project Manuscript)

Expected Change after Implementing Motivational Interviewing

Implementing motivational interviewing is expected to improve medication adherence behavior, which is indicated by measures including treatment failure rate, readmission rates, hospitalization rates, and mortality rates. The desired changes based on these measures include decreased treatment failure rate, reduced readmission rate, decreased hospitalization rates, and decreased mortality rate associated with schizophrenia. Per Aubeeluck et al. (2021), MI interventions significantly improved medication adherence in 5 RCTs and systolic blood pressure in 1 RCT. Khadoura et al. (2021) found that MI significantly improved medication adherence, self-efficacy, and intrinsic motivation for patients in the intervention group. According to Papus et al. (2022), MI improved medication adherence in 23 RCTs and risky behaviors and disease symptoms in 19 RCTs. Additionally, Zomahoun (2018) established that MI interventions might help improve medication adherence for chronic conditions in adults. The evidence indicates a positive relationship between motivational interviewing and medication adherence, although measures used vary for the different studies. (Week 6 Final DNP Project Manuscript)

References

https://www.ncbi.nlm.nih.gov/books/NBK20369/#:~:text=There%20are%20many%20different%20mental,or%20behaviors%20in%20distinct%20ways.

 
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Literature Review

Literature Review

(Literature Review)

Introduction

Falls are common in older adults, leading to serious injuries, including fractures and head injuries, and death in worst-case scenarios. Falls are also associated with disability and significant morbidity and mortality among older adults. Old age leads to overall poor physical and mental or cognitive status, which makes older adults prone to falls that cause physical injury and, in some instances, fear and psychological trauma. Statistically, a third of older adults experience at least one fall annually, while 10% fall multiple times yearly (Lloyd, 2021). Medical conditions increase the risk of falls, jeopardizing an older adult’s independence, and associated socioeconomic and personal consequences. Falls can occur at home or in any healthcare setting, including nursing homes. Hospitals are responsible for adopting interventions to minimize or prevent falls in older adults. Many interventions are adopted to prevent falls, including improving the environment and the terrain to make walking easy, providing non-slippery footwear, patient education, adequate lighting, installing handrails in hallways and bathrooms, and raising the bed to a comfortable height. This paper focuses on the role fall prevention interventions in reducing the risk factors of falls and associated effects among older adults. The primary themes addressed are; effects of falls on older adults, risk factors most frequently associated with falls in elderly patients, and impact of fall prevention programs on number of falls experienced by elderly patients. (Literature Review)

Literature Review

PICOT Question

Among older patients, do fall prevention interventions reduce the risk factors of falls and associated effects compared with no intervention? (Literature Review)

 

Primary Themes

Effects of Falls on Older Adults

Falls among older adults are one of the most prevalent and dangerous issues causing disabilities, physical injury, and cognitive impairment. Falls are directly correlated with mortality, morbidity, and decreased functionality. Falls are widespread among the elderly, kids, and athletes. Studies have indicated that a higher tendency to fall and, thus, a higher risk of injury is connected with medical comorbidities in the elderly (Appeadu & Bordoni, 2022). Falls are also linked to socioeconomic and personal effects, including direct and indirect healthcare costs such as paying for fall-related injury treatment and financial loss from the patient’s or the caregiver’s work absence to attend to the injury or impaired functionality. According to Appeadu and Bordoni (2022), the US incurs over $31 billion, which could rise to 74 billion by 2030, associated with falls among older adults 65 years and over. Conclusively, falls impact the patient and the healthcare system in multiple ways, including increasing healthcare costs, contributing to medical conditions, financial loss, and impaired functionality. Therefore, it is critical to prevent falls and reduce the risk of falls for hospitalized patients to promote their quality of care.

Falls lead to different injuries, including minor and major fractures and head injuries. Approximately 30%-50% are minor, 10% major injuries, and 1% hip fractures, with the last one increasing post-fall morbidity and mortality risk. Approximately 20% lead to serious injuries, including fractures in other body parts or head injuries. Studies have shown that, annually, fall-related injuries lead to over 800,000 hospitalizations, with 300,000 requiring hip fracture treatment (Vaishya & Vaish, 2020). Falls are estimated to be the leading cause of traumatic brain injury and associated deaths among older people aged 65 years and above. Repeated falls increase the risk of severe injury, hospitalization, and death because of frail body structures (Vaishya & Vaish, 2020). About half of the falls lead to an injury, with major ones including head injuries and fractures. Frailty rather than age determines the severity of an injury and associated consequences. In conclusion, falls cause different types of injuries that can lead to morbidity, disability, loss of function, and mortality among older adults. Therefore, preventing falls and their associated injuries is critical to promote patient safety and experience during their hospital stay. (Literature Review)

Literature Review

Risk Factors Most Frequently Associated with Falls in Older Patients

Inpatient falls, and fall-related injuries can be caused by various factors, including physical or cognitive impairments, environmental hazards, inadequate staff supervision, and age-related, such as hearing and vision impairment, vibration sensation and proprioceptive reduction, altered gait, and declining positional control. Age-related factors and changes do not cause falls directly but significantly contribute to most falls. Research shows that falls in older adults are also associated with physical diseases, medication side effects, cognitive deterioration, and environmental hazards (Vaishya & Vaish, 2020). According to Vaishya and Vaish (2020), environmental factors increase the risk of falling and can occur independently or interact with other factors, especially when postural control and mobility are needed, like walking on slippery and uneven surfaces. Maintaining balance becomes a problem as people age because of an impaired nervous system, which makes recovering balance challenging (Cuevas-Trisan, 2019). Furthermore, older age causes muscle weaknesses that make balancing and positioning difficult, leading to increased fall risk. Also, inadequate staffing or insufficient staff supervision can mean potential fall risks are not identified and addressed quickly enough (Vaishya & Vaish, 2020). In conclusion, inpatient falls, and fall-related injuries can be caused by a variety of factors, including physical or cognitive impairments, environmental hazards, and inadequate staff supervision. It is important to identify these potential causes to reduce the risk of falls and fall-related injuries. (Literature Review)

Impact of Fall Prevention Programs on Number of Falls Experienced by Older Patients

Falls prevention programs are implemented to reduce the risk of falls and fall-related injuries among hospitalized patients, especially older patients. There are many fall prevention programs, including patient education, hourly rounding, and medication management. Other interventions include reorganizing the Falls Committee, flagging high-risk patients, improving fall reports, increasing falls scrutiny, reorganizing leadership systems, standardizing fall prevention equipment, adapting to new hospital buildings, investigating root causes, and helping nurses think critically regarding risk. Additionally, falls prevention interventions can include alarms, fall risk identification, sitters, intentional rounding, patient education, physical restraints, environmental modifications, and non-slip socks. Studies indicate that fall prevention programs have varying effectiveness, but using several interventions at once increases the efficacy of fall prevention efforts. Based on research, patient education, medication management, and hourly rounding generate consistent fall prevention results and reduce risk factors associated with falls among older adults (Daniels, 2016; Mant et al., 2016; Goldsack, 2015; Walsh et al., 2018; LeLaurin & Shorr, 2019). In conclusion, there are many interventions to prevent fall risk, but with varying effectiveness. A nurse’s role is to conduct evidence-based research on various interventions and select the one with more benefits to the particular patient population. (Literature Review)

The following fall prevention interventions or programs are reviewed for their effectiveness in preventing risk factors of falls and associated effects among older adults:

Patient Education

Patient education helps influence patients towards the desired behavior and produces knowledge, attitude, and skills changes required to promote health and improve patient outcomes. Fall prevention education includes strategies such as increasing awareness of slippery surfaces, using equipment installed in hallways to aid walking, communicating with providers, and taking caution about medications that increase the risk of falling. Studies indicate that incorporating patient education into other fall prevention strategies helps reduce fall risks. Heng et al. (2020) explored the effectiveness of patient education in preventing falls among older adults. Findings indicate that direct face-to-face patient education, educational materials like handouts, pamphlets, brochures, hospital policies, procedures, and systems can help reduce falls and associated injuries. Fall prevention programs incorporating patient education reduce the risk of falling because patients are empowered and more aware of themselves and their surroundings. Heng et al. (2021) also explored patient education’s impact on fall rate and found that consistent, patient-centered education and small interactive groups helped prevent falls among hospitalized patients. Conclusively, patient education programs are effective in helping reduce the risk of falling among older adults, and studies recommend incorporating patient education into other fall prevention programs to increase effectiveness. (Literature Review)

Medication Management

Medication management includes strategies that engage patients and healthcare providers to establish a comprehensive, complete, and accurate medication list to help manage potential adverse events, side effects, and what to avoid to reduce the risk of complications. Hospitalized patients, particularly older adults, are under several medications, which increases the risk of medication-induced falls. Medication side effects that increase the risk of falling are often ignored when planning for fall prevention. Fall-risk-increasing drugs should be considered a significant risk factor during fall risk assessment in healthcare settings. About 47% of active substances used by inpatients increase the risk of falling because most affect the nervous and cardiovascular systems (Michalcova et al., 2020). Research shows that medication management can minimize side effects and interactions that contribute to falls. Michalcova et al. (2020) suggest adopting medication management programs such as preliminary categorizing fall-risk-increasing drugs (FRIDs) based on adverse drug effects to reduce fall risk. In support, Ming et al. (2021) report medication review as an effective approach to managing adverse drug reactions and enhancing drug safety among older patients to prevent falls and fall-related injuries among older adults. Medication review also helped reduce the severity of injuries and fall-related fractures (Ming et al.,2021). In conclusion, there are different medication management programs, including risk categorization of drugs according to their adverse effects and medication review of drugs that can help prevent medication-induced falls. Therefore, hospitals should increase awareness of medication-induced falls by adopting medication management programs to prevent falls and fall-related injuries. (Literature Review)

Hourly Rounding

Hourly rounding includes nurses and unlicensed assistive personnel conducting scheduled patient visits to perform interventions specific to or tailored to a particular hospitalized patient. Hourly rounding includes activities like nourishment, pain management, helping with elimination needs, range of motion, proper positioning, helping patients with applicable musculoskeletal needs, and room observation to ensure proper and adequate lighting, call bell and phone are within reach, medical equipment is functioning as expected, and walking areas or hallways are clutter-free (Shepard, 2015). Studies indicate that hourly rounding generates consistent fall prevention results and reduces risk factors contributing to falls and associated effects among older adults (Daniels, 2016; Mant et al., 2016; Goldsack, 2015; Walsh et al., 2018; LeLaurin & Shorr, 2019). According to Daniels (2016), purposeful and timely hourly rounding is effective in helping meet patient needs consistently, ensuring patient safety, lowering preventable events, and proactively addressing patient problems. Mant et al. (2016) also found that implementing hourly rounding effectively prevents fall-related incidents among older patients in acute care settings. Goldsack (2015) further supports this after finding in a pilot test that fall rate was considerably lower, at 1.3 falls/1,000 patient days after implementing hourly rounding during the test period. Furthermore, Walsh et al. (2018) found that when nurses began addressing fall risk during hourly rounds, the fall rate significantly declined, implying hourly rounds’ effectiveness in reducing fall risk among inpatients. Consistently, Manges et al. (2020) found that hourly rounding improved care quality, patient satisfaction, and patient empowerment and helped decrease patient fall rates. In conclusion, hourly rounding is an effective approach to preventing falls among older patients. Therefore, hospitals and nurse leadership should implement intentional and purposeful hourly rounding to reduce risk factors contributing to falls in older adults and associated effects such as disability, loss of independence, and increased healthcare costs due to injury treatment. (Literature Review)

Others Interventions

Besides patient education, medication management, and hourly rounding, other fall prevention interventions can be adopted to help reduce the risk of falling among older adults. These interventions include reorganizing the Falls Committee, flagging high-risk patients, improving fall reports, increasing falls scrutiny, reorganizing leadership systems, standardizing fall prevention equipment, adapting to the new hospital building, investigating root causes, educating patients, and helping nurses think critically regarding risk in reducing patient falls. Walsh et al. (2018) found that implementing these interventions incrementally reduced the fall rate from 3.07 to 2.22 per 1000 patient days and injury rate from 0.77 to 0.65 per 1000 patient days. LeLaurin & Shorr (2019) investigated the effectiveness of alarms, fall risk identification, sitters, intentional rounding, patient education, physical restraints, environmental modifications, and non-slip socks and found that these interventions, coupled with intentional rounding, enhanced patient satisfaction and minimized patient harm. However, these studies indicate that other interventions have moderate effects on fall prevention, associated injuries, morbidity, and mortality and should not be implemented as stand-alone interventions. In conclusion, multiple fall prevention programs are implemented in hospitals, but research shows most fall prevention programs have moderate effects on fall prevention. Therefore, hospitals should consider adopting various interventions to increase the effectiveness of fall prevention efforts in healthcare settings. (Literature Review)

Conclusion

Patient falls are a significant problem in US hospitals, especially among older adults at increased risk of falling due to age-related factors, environmental factors, medical conditions, and frail bodies. Falls lead to injuries and contribute considerably to subsequent morbidity and mortality among hospitalized patients. Many interventions currently used to prevent falls indicate moderate benefits and unknown sustainability. Reviewed articles provide consistent results showing patient education, medication management, and hourly rounding as effective in reducing the risk of patient falls and associated effects, promoting patient safety, and improving patient experience, outcome, and satisfaction. (Literature Review)

References

Appeadu, M. K., & Bordoni, B. (2022). Falls and fall prevention in the elderly. In StatPearls [Internet]. StatPearls Publishing.

Cuevas-Trisan, R. (2019). Balance problems and fall risks in the elderly. Clinics in geriatric medicine35(2), 173-183.

Daniels J. F. (2016). Purposeful and timely nursing rounds: a best practice implementation project. JBI database of systematic reviews and implementation reports, 14(1), 248–267. https://doi.org/10.11124/jbisrir-2016-2537

Goldsack, J., Bergey, M., Mascioli, S., & Cunningham, J. (2015). Hourly rounding and patient falls: what factors boost success?. Nursing45(2), 25–30. https://doi.org/10.1097/01.NURSE.0000459798.79840.95

Heng, H., Jazayeri, D., Shaw, L., Kiegaldie, D., Hill, A. M., & Morris, M. E. (2020). Hospital falls prevention with patient education: a scoping review. BMC geriatrics20(1), 140. https://doi.org/10.1186/s12877-020-01515-w

Heng, H., Slade, S. C., Jazayeri, D., Jones, C., Hill, A. M., Kiegaldie, D., Shorr, R. I., & Morris, M. E. (2021). Patient Perspectives on Hospital Falls Prevention Education. Frontiers in public health9, 592440. https://doi.org/10.3389/fpubh.2021.592440

LeLaurin, J. H., & Shorr, R. I. (2019). Preventing Falls in Hospitalized Patients: State of the Science. Clinics in geriatric medicine35(2), 273–283. https://doi.org/10.1016/j.cger.2019.01.007

Lloyd, S. L. (2021). Hourly rounding to reduce patient falls – A quality improvement project. University of Texas.

Manges, M. E., Zuver, M. C., Mack, K., & Abraham, S. P. (2020). hourly rounding and medical-surgical patient falls: A review of the literature. International Journal of Science and Research Methodology.

Mant, T., Dunning, T., & Hutchinson, A. (2016). The clinical effectiveness of hourly rounding on fall-related incidents involving adult patients in an acute care setting: a systematic review. JBI Evidence Synthesis10(56), 1-12.

Michalcova, J., Vasut, K., Airaksinen, M., & Bielakova, K. (2020). Inclusion of medication-related fall risk in fall risk assessment tool in geriatric care units. BMC geriatrics20(1), 1-11.

Ming, Y., Zecevic, A. A., Hunter, S. W., Miao, W., & Tirona, R. G. (2021). Medication Review in Preventing Older Adults’ Fall-Related Injury: a Systematic Review & Meta-Analysis. Canadian geriatrics journal : CGJ24(3), 237–250. https://doi.org/10.5770/cgj.24.478

Shepard, L. H. (2015). Stop going in circles! Break the barriers to hourly rounding. Nursing management44(2), 13-15.

Vaishya, R., & Vaish, A. (2020). Falls in Older Adults are Serious. Indian journal of orthopaedics54(1), 69–74. https://doi.org/10.1007/s43465-019-00037-x

Walsh, C. M., Liang, L. J., Grogan, T., Coles, C., McNair, N., & Nuckols, T. K. (2018). Temporal Trends in Fall Rates with the Implementation of a Multifaceted Fall Prevention Program: Persistence Pays Off. Joint Commission journal on quality and patient safety44(2), 75–83. https://doi.org/10.1016/j.jcjq.2017.08.009

 
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